Amino Acid Catabolism

Question 1

What are the two major categories amino acid intermediates?

Answer 1

Glucogenic

Ketogenic

Question 2

What is a glucogenic AA intermediate?

Answer 2

A TCA cycle intermediate that can be shunted to gluconeogenesis

Question 3

What is a ketogenic amino acid intermediate?

Answer 3

AcetylCoA derivatives that can be used for ketone body synthesis

Question 4

Almost all of the AA intermediates are at least partially ___.

Answer 4

Glucogenic

Question 5

What are the 4 glugogenic and ketogenic products?

Answer 5

3 aromatics

Ile

Question 6

What are the 2 purely ketogenic products?

Answer 6

Leu

Lys

Question 7

Breakdown of Met results in which amino acid?

Answer 7

Cysteine

Question 8

Breakdown of phenylalanine yields what?

Answer 8

Tyrosine

Question 9

The key to interconversion of amino acids and carbohydrates lies in the interrelationship between ___ and ___.

Answer 9

Amino acids

alpha-keto acids

Question 10

What are the two ketogenic metabolites of amino acid metabolism?

Answer 10

AcetoacetylCoA

AcetylCoA

Question 11

What are the 3 carbon amino acids?

Answer 11

Ala
Ser
Cys
Trp

Question 12

What is a 3 carbon alpha-keto acid?

Answer 12

Pyruvate

Question 13

Alanine is very similar to what?

Answer 13

Pyruvate

Question 14

What 4 things are converted to pyruvate?

Answer 14

Ala
Ser
Cys
Non-ring portion of Trp

Question 15

Asp and Asn are metabolized into what?

Answer 15

Oxaloacetate (4 carbon alpha-keto acid)

Question 16

Aspartate is very similar to what?

Answer 16

Oxaloacetate

Question 17

Glutamate is very similar to what?

Answer 17

alpha-ketoglutarate

Question 18

What 5 amino acids are first converted to Glu before alpha-ketoglutarate?

Answer 18

Gln
Pro
Arg
His
Glu