amboss misoprost, ocreatodie

Question 1

What must to exclude befo prescribin misoprostol?

Answer 1

pregnancy. CONTRAINDICATED IN PREGANACY

Question 2

Misoprostol, analog of what?

Answer 2

PGE1 analog

Question 3

Misoprostol. effect on stomach?

Answer 3

Gastric antisecretory agent with protective effects on the gastroduodenal mucosa
AKA
incr. production and secretion of gastric mucous barrier
and
Decr. of acid production

Question 4

Misoprostol. indications?

Answer 4

PREVENTION of NSAIDs induced ulcers. (Nsaids block PGE1 production that protects mucosa)

Short-term treatment of gastric and duodenal ulcers

Termination of pregnancy/labor induction
Prevention or treatment of serious postpartum hemorrhage

Question 5

Misoprostol. Adverse?

Answer 5

Diarrhea. contraindication in women of childbearing potential.

Question 6

Octreotide what type of drug?

Answer 6

long-lasting somatostatin analog (Somatostatin Agonists)

Question 7

octreotide mechanism?

Answer 7

inhibits secretion of various splanchnic vasodilatory hormones.

Question 8

inhibits secretion of various splanchnic vasodilatory hormones. Drug?

Answer 8

octreotide

Question 9

Octreotide indications?

Answer 9

Acute variceal bleeding (pvz kai yra anastomozes del portal hypertension);
acromegaly;
VIPoma;
carcinoid tumors

Question 10

Octreotide adverse?

Answer 10

nausea, cramps, steatorrhea.

Increased risk of cholelithiasis due to CCK inhibition

Question 11

Acute variceal bleeding (pvz kai yra anastomozes del portal hypertension);
acromegaly;
VIPoma;
carcinoid tumors

DRUG?

Answer 11

Octreotide

Question 12

Sucralfate. mechanism?

Answer 12

A sucrose sulfate-aluminum complex that reacts with HCl in an acidic environment to create a protective barrier over the gastric/duodenal mucosa

Question 13

sucralfate should not be taken simultaneously with what medications?

Answer 13

Should not be taken simultaneously with a PPI or H2 blocker

Question 14

Sucralfate action as buffer?

Answer 14

Acts as an acid buffer and promotes HCO3 production –> restores pH

Question 15

Sucralfate indications?

Answer 15

Short-term treatment of gastric ulcer and duodenal ulcers

Question 16

why do not prescribe sucralfate with PPI or H2 blocker?

Answer 16

because sucralfate need acid environment

Question 17

Bismuth. for what diarrhea?

Answer 17

prevent travelers diarhhea

Question 18

Bismuth. what antiulcer use?

Answer 18

as a part of h pylori erradicattion. Use for duodenal ulcers (h pylori dazniau sukelia duodenal)

Question 19

Bismuth. agent for what?

Answer 19

Antidiarrhea agent; antidyspepsia agent;

internal deodorant

Question 20

Reduction of flatulence or stool odor from a colostomy or ileostomy. what to use?

Answer 20

bismuth (named as internal deodorant)

Question 21

Dyspepsia (Upset Stomach). Medication?

Answer 21

bismuth.

symptomatic relief of dyspepsia (e.g., upset stomach, nausea, heartburn, fullness, belching, gas) secondary to overindulgence in food and drink.