Ambiguous Genitalia Flashcards
3 things about hermaphroditism…
Has BOTH ovarian and testicular tissue
Internal & external genitalia variable
46, XX karyotype or mosaics (46, XX/46, XY)
What are the 2 kinds of ambiguous genitalia?
Hermaphroditism and female pseudohermaphroties
Female pseudohermaphroties has what kind of karyotype?
46, XX
What is the relationship between female pseudohermaphroties and androgen?
Increased production of androgens
Androgen therapy for mother
What is the relationship between female pseudohermaphroties and external genitalia?
Masculinization of external genitalia
Ex. Enlarged clitoris, abnormalities of urogenital sinus & partial fusion of the labia majora
When using ultrasound for ambiguous genitalia, what should you look for?
The presence or absence of a uterus, vagina, & ovaries
When NORMAL female parts are seen on a fetus, what sign will you see?
The hamburger sign
When NORMAL male parts are seen on a fetus, what sign will you see?
The turtle sign
