Alzheimers (4)

Question 1

What is Alzheimer’s disease?

Answer 1

It is a neurodegenerative disease caused by the abnormal accumulation of proteins in the brain (Amyloid and Tau).

Question 2

What are the three stages of Alzheimer’s?

Answer 2

1. Presymptomatic.
2. Prodromal.
3. Dementia.

Question 3

Where do amyloid and tau develop?

Answer 3

Amyloid – outside the cell.
Tau – inside the cell.

Question 4

What is the STM binding test and was does it assess?

Answer 4

• Involves colour and shape remembrance and matching colours and shapes.
• The ability to integrate information into the STM and hold information as individual items is assessed.
• Failure on this task indicates a likelihood to develop dementia.

Question 5

What radiotracers have allowed AD to be detected well before symptoms become apparent?

Answer 5

PET.

Question 6

What aspect/syndrome of AD does the STM task assess?

Answer 6

Brain connectivity.

Question 7

What methods use the eyes to measure AD?

Answer 7

Pupilometry and eye-tracking.

Question 8

Which can you use to investigate the association of brain connectivity and integrative memory functions AD? (3)

Answer 8

• EEG.
• DTI.
• MRI.