Alzheimer's Drugs

Question 1

noncompetitive AChE inhibitors
Adverse: GI cramping, abnormal dreams
Caution: with bradycardia, syncope

Answer 1

Donepezil (Aricept)
rivastigmine (Exelon)
galantamine (Razadyne)

Question 2

noncompetitive antagonist for the NMDA receptor
sits on the Mg2+ site in the channel
neuroprotective preventing excessive excitability
Adverse: headache, dizziness
-can give with Donepezil

Answer 2

memantine (Namenda)