ALU 301 Chapter 3 Quiz Flashcards
The triad of positive rheumatoid factor, enlarged spleen, and neutropenia is:
- Caplan’s syndrome
- Felty’s syndrome
- Sjogren’s syndrome
- Still’s disease
Felty’s syndrome
All of the following statements regarding laboratory testing on individuals with rheumatoid arthritis are correct EXCEPT:
- globulins are often elevated
- cholesterol may be low in late stage disease
- The inflammatory process may elevate HDL
- low albumin is a poor prognostic indicator
The inflammatory process may elevate HDL
The joints most commonly affected by rheumatoid arthritis include all of the following EXCEPT:
- elbows
- knees
- shoulders
- hips
hips
All of the following laboratory tests are commonly used for the diagnosis and monitoring of rheumatoid arthritis EXCEPT:
- gamma-glutamyltransferase (GGT)
- rheumatoid factor
- anti-cyclic citrullinated peptide (anti-CCP)
- C-reative protein (CRP)
GGT
The hallmark of current therapy for rheumatoid arthritis is the use of:
- non-steroidal anti=inflammatory drugs (NSAID’s)
- cyclooxygenase inhibitors (COXIB’s)
- disease modifying anti-rheumatic drugs (DMARD’s)
- corticosteroids
disease modifying anti-rheumatic drugs - DMARD’s)
A chronic inflammatory polyarthritis of unknown etiology is:
- viral arthritis
- rheumatoid arthritis
- gouty arthritis
- osteoarthritis
rheumatoid arthritis
All of the following are possible etiologies of rheumatoid arthritis EXCEPT:
- genetics
- infection
- cigarette smoking
- oral contraceptives
oral contraceptives
Which of the following medications are used to slow the progression of joint erosion in rheumatoid arthritis?
A - Biologics
B - disease modifying anti-rheumatic drugs (DMARD’s)
C- non-steroidal anti-inflammatory drugs (NSAID’s)
A and B only
A and C only
B and C only
A, B, and C are all correct
-
A and B only
The most probable theory is that rheumatoid arthritis is the result of:
- infection
- smoking
- multiple gene dysfunction
- decaffeinated coffee consumption
multiple gene dysfunction
Rheumatoid arthritis commonly affects all of the following joints EXCEPT:
- shoulders
- neck
- ankles
- wrists
neck
Initial assessment of rheumatoid arthritis includes which of the following?
A - blood chemistries
B - radiographs of affected joints
C - anti-cyclic citrullinated peptide antibody (ACPA)
A only is correct
A and B are correct
B and C are correct
A, B, and C are correct
A, B, and C are all correct
Which of the following labs are typical findings in those with rheumatoid arthritis?
A - elevated white blood count
B - elevated globulins
C - mild thrombocytosis
A and B only are correct
A and C are correct
B and C are correct
A, B, and C are all correct
B and C are correct
The most sensitive tool for joint assessment is:
- xray
- MRI
- ultrasound
- CT scan
MRI
The medical treatment considered to be the gold standard for moderate to severe rheumatoid arthritis is:
- methotrexate (MTX)
- sulfasalazine
- hydroxychloroquine
- leflunomide
methotrexate
Which of the following accounts for the greatest number of deaths associated with rheumatoid arthritis?
- infection
- renal disease
- pulmonary disease
- cardiovascular disease
cardiovascular disease
Which of the following statements regarding synovial joints is/are correct?
A- it is comprised of two bones held together by a fibrous capsule
B - the synovium provides nutrients to avascular cartilage
C - synovial fluid between the bones allows frictionless movement of the joint
A only is correct
A and C are correct
B and C are correct
A, B, and C are all correct
A, B, and C are all correct
Elevated rheumatoid factor (RF) can be seen in all of the following diseases EXCEPT:
- Sjogren’s syndrome
- mixed connective tissue disease
- systemic lupus erythematous (SLE)
- osteoarthritis
osteoarthritis
Mild rheumatoid arthritis is characterized by all of the following EXCEPT:
- joint pain
- mild morning stiffness
- elevated ESR
- extra articular manifestations
extra articular manifestations
Which of the following cells infiltrate the subintimal area of the synovium in those with rheumatoid arthritis?
A- T-lymphocytes
B - macrophages
C - cytokines
A only is correct
A and B are correct
B and C are correct
A, B, and C are all correct
A and B are correct
The condition that is the result of inflammation of the synovial tissue, microvascular injury and the profound proliferation and hypertrophy of the synovial tissue is:
- pannus formation
- morning stiffness
- vasculitis
- osteoporosis
pannus formation
