Altitude Flashcards

1
Q

What does acute ascent to altitude result in?

A

Environmental hypoxia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the reduction in the amount of oxygen due to

A

Reduced barometric pressure at increasing altitudes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

How does barometric pressure change partial pressure of inspired oxygen

A

The lower barometric pressure reduces the partial pressure of inspired oxygen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Hypobaric Hypoxia

A

The hypoxia associated with terrestrial altitude exposure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the percentage of oxygen in ambient air

A

Constant at 20.93% regardless of the altitude

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

T/F the percentage of oxygen in boulders is less than at sea level

A

False

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the PiO2 in boulder (1630m)

A

122 mmHg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the PiO2 at sea level

A

149 mmHg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What three parameters need to be considered to to calculate PiO2

A
  1. Barometric pressure
  2. Water vapor pressure
  3. Percentage of oxygen in the environment
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is barometric pressure dependent on

A

Altitude

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is water vapor pressure (PH2O) in inspired air

A

47 mmHg independent on altitude

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Sea level PiO2 calculation

A

(760 mmHg - 47 mmHg) * 0.2093= 149 mmHg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

How does acute reduction in PiO2 affect oxygen levels in the blood?

A

Reduced PiO2 leads to a decrease in alveolar partial pressure of oxygen which leads to a reduction in the partial pressure of oxygen in arterial blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the pressure of oxygen in arterial blood (PaO2) determinant of?

A

Major determinant of arterial hemoglobin O2 saturation (SaO2)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What happens at the top of the hemoglobin oxygen dissociation curve?

A

Small changes in PaO2 have minimal effect on SaO2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What happens at the steep portion of the hemoglobin oxygen dissociation curve?

A

Small changes in PaO2 have large effects of SaO2

17
Q

What is arterial oxygen content (CaO2) determined by

A

Hemoglobin concentration, SaO2, and the amount of oxygen dissolved in the plasma

18
Q

What is PaO2’s influence on SaO2

A

PaO2 determines the amount of oxygen dissolved in the plasma which reflects the saturation

19
Q

What is the difference between the amount of O2 dissolved in the plasma compared to bound to hemoglobin

A

The amount of O2 dissolved in plasma is extreamly small compared to the amount bound to hemoglobin

20
Q

What physiological effects occur in response to the decrease in PaO2, SaO2 and CaO2 with altitude

A

Impacts the cardiovascular, respiratory, and immune systems as well as impacts substrate utilization

21
Q

What happens to VO2 max at acute altitude exposure

A

VO2 max is reduced with the severity of the reduction greater at higher elevations.

22
Q

What effect does the reduction of VO2 max have on intensity

A

Increases the relative intensity of any given absolute power output at altitude

23
Q

Difference in VO2 max differences depending on training status at altitude

A

Trained athletes have a greater reduction in VO2 max

24
Q

What response does heart rate have at acute altitude exposure

A

Increase in resting heart rate and an elevation in heart rate at any given absolute submaximal power output

25
Q

What happens to maximal heart rate at acute altitude exposure?

A

No change

26
Q

How is the ventilatory response regulated at acute altitude

A

Peripheral chemoreceptors that reside in the aortic and carotid bodies respond to low PaO2 during hypoxia

27
Q

What happens to ventilation patterns at altitude?

A

Decrease PaO2 results in an increase in ventilation at rest and all absolute workloads

28
Q

What changes happen to substrate utilization at altitude

A

Increases in carbohydrate utilization during absolute submaximal exercise intensities

29
Q

MAP response to acute altitude exposure

A

MAP may decrease due to reductions in TRP and blood pressure

30
Q

Hypoxia in the lab setting

A

<20.93 % gas mixture

31
Q

Normobaric hypoxia

A

Pressure is normal but the PiO2 is reduced due to artificial reduction in the percentage of inspired oxygen

32
Q

What components of arterial oxygen content would be most affected by blood doping

A

Hemoglobin concentration increases

33
Q

What components of arterial oxygen content would be relatively unaffected by blood doping

A

Hemoglobin saturation and the rate of hemoglobin unloading to the tissues

34
Q

2 mechanisms which increased sympathetic activity may increase oxygen delivery with acute altitude exposure

A

Increased HR and ventilation; increase BP with exercise