Altered Immunological Activity Diseases Flashcards
What % of SLE patients will develop pleural or pulmonary disease?
50%
What is the M/C pulmonary involvement with SLE individuals?
pleural disease
What is the cause of the “shrinking lung syndrome” in SLE patients?
diaphragmatic dysfunction
What is the M/C/C of death in SLE patients?
renal failure
Extraarticular (eg. pulmonary) manifestations of rheumatoid disease is M/C in which gender?
men
What is the water bottle sign in chest radiology?
The appearance of the heart in cases of cardiomegaly or pericardial effusion.
What is the M/C pulmonary manifestation of RA?
interstitial pneumonia and fibrosis
How do pulmonary rheumatoid nodules clinically present and where are they M/C located?
M/C asymptomatic.
M/C located in lung periphery and bases.
Caplan’s syndrome has a predominance for which lobe?
upper lobe
Progressive systemic sclerosis M/C affects which gender?
women
What % of scleroderma patients have pulmonary disease at some point in their life?
75%
Scleroderma has a predominance for which lobe?
lower lobe
True or False: enlarged mediastinal nodes are rare in scleroderma.
False - seen in 60%
What are the x-ray findings of scleroderma?
- progressive loss of lung volume d/t progressive fibrosis
- spontaneous pneumothorax d/t large cysts
- 50% enlarged central pulmonary arteries & R ventricular dilation d/t pulmonary arterial HTN
What is the M/C/C of death in a patient with relapsing polychondritis?
recurrent pneumonia
How commonly is the upper airway affected in relapsing polychondritis?
50%
What % of Wegener’s granulomatosis patients have lung involvement. What % involves the upper respiratory tract?
90% lung involvement
~100% upper respiratory tract involved
What is the M/C radiographic finding associated with Wegener’s?
multiple lung nodules/masses
What is the headcheese sign what condition is it a hallmark sign for?
Hypersensitivity pneumonitis (aka extrinsic allergic alveolitis)
Which organism is most commonly inhaled in farmer’s lung?
actinomyces
What is Loeffler’s syndrome?
What unique radiographic feature is seen in Loeffler’s syndrome? Which other condition also presents with this finding?
aka. Simple eosinophilic lung disease
Self-limiting disease caused by hypersensitivity to drug therapy.
Reverse bat-wing appearance –> peripheral opacification
Also seen in chronic eosinophilic pneumonia
What is the triad associated with Goodpasture’s syndrome?
Which gender does it affect most?
Triad
a) Glomerulonephritis
b) Pulmonary hemorrhage
c) Fe anemia
M:F = 4:1
