Alteration in Acid/Base Balance Flashcards
How does the body repair a respiratory issue?
Kidneys
How does the body repair a metabolic issue?
Lungs
How is pH of the body maintained?
Buffers via elimination of acids through lungs and kidneys
What are the chemical buffers of the body?
CO2 (acidic)
HCO3 (alkalotic)
How do the lungs compensate?
By controlling the amount of CO2 in the blood
Immediate response
How do the kidneys compensate?
By changing the rate of excretion or retention of H+ and HCO3- ions
“Slow” response
What will happen if the metabolic side is too acidic?
Body will breathe faster and blow off CO2 (acid)
What will happen if the metabolic side is too alkalotic?
Body will slow down breathing and hold on to CO2 (acidic)
What happens when the body is too alkalotic?
At distal tubules (where reabsorption takes place), the body will reabsorb H+ and excrete HCO3 (alkalotic)
What happens when the body is too acidic?
At distal tubules, the body will reabsorb HCO3 and excrete H+
What is chemical regulation?
Plasma protein buffer where albumin, fibrinogen, prothrombin, and gamma globulin can bind with H+ to correct acidosis or alkalosis
(Limited binding capacity)
What is biological regulation?
When H+ ions are absorbed or released by body cells
H+ must be changed with another + ion (often K+)
When can biological regulation occur?
After short term chemical buffering
Takes 2-4 hours
What are the physiological buffers?
Lungs - rapid adaptation
Kidneys - slower
What is a normal pH?
7.35-7.45