Alpha feto-protein (AFP) Flashcards

1
Q

what is AFP?

A

protein produced by developing fetus

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2
Q

what causes an increased AFP?

A
  • NTDs (meningocele, myelomeningocele, anencephaly)
  • abdominal wall defects (omphalocele, gastrochisis)
  • multiple pregnancy
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3
Q

what causes a decreased AFP?

A
  • Down’s syndrome
  • Trisomy 18
  • maternal DM
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