Alpha-1 blockers, 5 alpha reductase inhibitors, antiarrhythmics, cardiac glycoside, anti-hyperlipidemics, anti acne Flashcards
Minipress generic and I
Prazosin HTN only
Uroxatral generic and TC and I
alfuzosin; BPH symptoms
Rapaflo generic, TC, I
siloDosin, BPH symptoms
Proscar dosage form/ strength and I
finasteride- 5mg tab; BPH symptoms
Propecia doage form/ strength and I
finasteride 1 mg tab; I alopecia
Jalyn
dutasteride + tamsulosin
dutasteride + tamsulosin
Jalyn
BBW for antiarrythmics
proarrythmic
Pacerone
amiodarone
Cordarone
amiodarone
amiodarone NB and TC
Pacerone or cordarone
doxazosin and terazosin TC and NB
Cardura (doxazosin), alpha 1 blocker; HTN and BPH
Cardura generic and I
doxazosin, HTN and BPH
Multaq
dronedarone
Tikosyn
dofetilide
Norpace
disopyramide
Tambocor
flecainide
Rythmol
propafenone
mexiletine TC
antiarrhythmic
Tikosyn BBW
must monitor continuously for 3days (dofetilide has highest incidence of proarrhythmic effects)
only use in pts. with life-threatening arrhythmias (drug of LAST RESORT!)
dronedarone NB and BBW
Multaq
Cordarone generic and BBW
BBW:
only use in pts. with life-threatening arrhythmias
may cause pulmonary toxicity, specifically alveolitis = inflammation of the alveoli
which antiarrythmic may cause phototoxicity
amiodarone- Cordarone, Pacerone
normal digoxin serum level for heart failure
0.8-1.5 ng/ml
normal digoxin serum level for arrhythmias
1.5 – 2 ng/mL
dosage forms of digoxin
tab (Lanoxin) - 0.125 mg, 0.25 mg
oral solution – 0.05mg/mL
parenteral injection – 0.25mg/mL
DI of digoxin
QD
Anti-hyperlipidemics classes
- HMG co-A reductase inhibitors
- Fibric acid derivatives
- Bile acid sequestrants
- cholesterol absorption inhibitors
normal levels: HDL LDL (healthy) LDL (at risk) triglycerides
HDL: >40mg/dL
LDL (healthy): <150mg/dL
can cause rhabdomyolysis
HMG co-a reductase inhibitors
disintegration or dissolution of muscle tissue
rhabdomyolysis
pravastatin
Pravachol
simvastatin
Zocor
pitavastatin
Livalo
Altoprev generic, dosage form and dietary info
lovastatin ER tab *empty stomach
Mevacor generic, dosage form and dietary info
lovastatin IR tab *with food
lovastatin NB
Altoprev and Mevacor
Livalo
pitavastatin
Lipitor
atorvastatin
Crestor
rosuvastatin
Lescol/ XL dosage form
fluvastatin: IR cap, ER tab
which antihyperlipidemics are taken with food
Lofibra, Simcor, Advicor
Lopid generic and dietary info
gemfibrozil, empty stomach,
fenofibrate NBs
- Tricor
- Triglide
- Antara
- Lofibra
fenofibrate taken with food
Lofibra
Questran
cholestyramine
Welchol
colesevelam
Colestid
colestipol
Welchol generic, dosage form, dosing interval
colesevelam, tab: (625mg) 6 QD or 3 BID
powder: 3.75g QD or 1.875g BID
cholestyramine NBs
Questran and Prevalite
cholesterol absorption inhibitor
ezetimibe- Zetia
Vytorin
ezetimibe and simvastatin
Advicor
niacin and lovastatin
Simcor
niacin and simvastatin