Allergy and asthma Flashcards
Race differences + asthma
4.6/10.000 black woman died of asthma compared to 2.7/10.000 white woman.
incidence rate ratio (IRR) + asthma
IRR were increased among woman who reported childhood abuse.
IRR for woman who felt in danger in the home in addition to being abused as children were higher than those for woman who were abused but did not feel in danger.
Physical abuse + asthma
Exposure to physical abuse during childhood was associated with an increased incidence for adult-onset asthma of greater than 20%. The risk was higher among women who also felt in danger in the home as a child.
IRR + sexual abuse
IRR were weaker for sexual abuse during childhood, and there was little evidence that abuse during adolescence increased asthma incidence.
Allergies
An immune-mediated hypersensitivity reaction
Different types of allergies
Asthma bronchial: 2-10% Exzema: 10-20% Pollen Food: 1-2% Drug: 5-20% Anaphylaxis <1%
Allergies + personality (early studies)
Neurotic trait = higher probability to get allergy as behavioral inhibition, introversion, social anxiety.
Alexithymia, passive, avoidance coping, high depndence
Allergies and personality (later studies)
higher hostility, high perfectionism, high need for being loved and need for approval, high rates of emotional coping, less satisfaction with family life, better financial situation (they are still less satisfies)
psychophysiological approaches to allergies
Dysfunction in the HPA axis
Dominance of the right hemisphere (alteration of laterality)
Bidirectional connection between the CNS and immune system components
Psychodynamic approach to allergies
Communication through the allergic symptom
Symptom as symbol of a psychological problem
Allergies + psychopathologies
There is a high correlation between allergic symptoms and anxiety, depression, exhaustion.
More than 50% of patient hd mild, medium or severe depression. (the direction can also go the other way around, because 40% of those who is depressed also get allergic symptoms)
Most frequent:
- panic disorder
- anxiety disorder
- phobias
- somatization problems
- sleep problems
Two types of pediatric asthma
Extrinsic and intrinsic
Extrinsic asthma
Atopic - associated with evidence of allergen sensitization.
Intrinsic asthma
Nonatopic - is brought by exercise or other triggers but does not have an obvious extrinsic trigger.
Symptoms of asthma
Shortness of breath Cough Wheezing Chest tightness Agitation HEart rate Respiratory rate
Prevalence of asthma
0-17 y: boys have higher rate
> 18 y: woman have higher rate
Psychosocial factor of asthma
- anxiety and fear of having an attack
- Uncertainty, because it is unpredictable and uncontrollable (learned helplessness)
- Unreleated emotional reactions and problems lead to more frequent visits to emergencies.
Environmental risk factors of asthma
house dust, cat and dog allergens, as well as exposure to environmental tobacco smoke in children over 6 years.
In children younger than 6 years, exposure to pet had a protective effect.
psychosocial risk factors of asthma
- preterm birth and eight gain predict childhood asthma
- Childhood physical and sexual abuse
- intimate partner violence exposure of the other (at 7month of age)