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6. SUGAR > Aldosterone > Flashcards

Aldosterone Flashcards

1
Q

What is aldosterone?

What is it produced by?

A

Steroid hormone

Zona glomerulosa cells in adrenal cortex of adrenal glands

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2
Q

What does Aldosterone act on?

A

Principal cells of the collecting duct

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3
Q

What does aldosterone stimulate?

A

The transcription of ENaC to increase Na+ reabsorption and H2O reabsorption

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4
Q

Is aldosterone faster or slower than ADH? Why?

A

More slowly than ADH as it induces changes in gene expression and protein synthesis

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5
Q

What does ANP do?

A

Control Na+ reabsorption

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6
Q

What cells synthesise and secrete ANP?

A

Cells in the cardiac atria

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7
Q

How does ANP control Na+ reabsorption?

A

Inhibits Na+ reabsorption by blocking the ENaC in collecting ducts

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8
Q

What are the functions of ANP?

A

Decrease ENaC
Decrease Aldosterone
Increase GFR (for Na+ excretion) - dilate AA
(Decrease BP)

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9
Q

What does angiotensin 2 cause to happen?

A

Stimulates aldosterone
Vasoconstriction efferent arteriole
Increased Na+ reabsorption in PCT
Stimulate ADH from pos pit

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6. SUGAR (14 decks)

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