Alcohol & SA Flashcards
Alcohol withdrawal: onset, sx, mx
Onset: within 4-12 hrs of cessation
Sx: tremulousness, sweating, N/V, mood, hyperacusis, ANS hyperactivity, sleep, psychomotor agitation
Mx: IM lorazepam or chlordiazepoxide
Alcoholic hallucinosis: onset, sx, mx
Onset: within 12 hrs of cessation
Sx: hallucination (visual > auditory & tactile), secondary delusions
Mx: antipsychotics e.g. haloperidol x6m
Alcohol withdrawal seizures: onset, RF
GTC
Onset: within 24 hrs of cessation
RF: previous hx, concurrent epilepsy, low K or Mg
Delirium tremens: sx, mx
Sx: vivid hallucinations, altered LOC & cognitive impairment, tremor, ANS arousal (sweating, tachycardia, HT, fever), paranoid delusions
Mx: large dose BZD (chlordiazepoxide or lorazepam), antipsychotic (haloperidol), large dose parenteral thiamine
Wernicke encephalopathy: cause, sx, mx
Thiamine deficiency (malabsorption -> acute brain damage) Clinical triad: delirium, ophthalmoplegia, ataxia Mx: parenteral thiamine BEFORE glucose
Korsakoff’s syndrome: sx, mx
Chronic state after Wernicke (irreversible)
Sx: amnesia, confabulation, poverty of speech, frontal lobe dysfunction, psychotic symptoms
Mx: lifelong oral thiamine
Alcoholic dementia / amnesic syndrome: epidemiology, sx
10% of all dementia
Sx: disoriented to time, confabulation, impaired short term memory
How to diagnose alcohol use disorder?
3 in past 12m
1) Craving
2) x control
3) Primacy
4) Tolerance
5) Withdrawal
6) Knowledge of harmful consequences (health, physical hazards)
How to manage alcohol use disorder?
Controlled drinking VS abstinence
Detox: chlordiazepoxide (taper down in 1st week)
Thiamine BEFORE glucose
Optional: disulfaram, naltrexone
Psychotherapy: CBT, motivational interviewing, AA
Cannabis intoxication
Physical: tachycardia, dry mouth, conjunctival injection, increased appetite
Psychological: euphoria, sedation, impaired judgment / memory / motor performance, distorted sensory perception, sensation of slowed time, asocial
Functional: amotivational syndrome
Cannabis withdrawal
Mood: irritable, anxious, depressed, restless
Poor sleep & appetite
Physical: abdominal pain, tremor, sweating/chills, headache
Examples of psychostimulants
Cocaine, meth, ecstasy
Examples of CNS depressants
Alcohol, BZD, Z drugs, heroin
What are the sx of psychostimulant intoxication?
Increased excitement, talkativeness, confidence Hand tremor Tachycardia, HT, palpitation Dilated pupils Sweating
What are the sx of psychostimulant withdrawal?
Depression
Psychomotor retardation