Alcohol Flashcards

1
Q

What is ethanol?

A

CH3CH2OH, alcohol
Colourless, volatile liquid
Also found in many other products e.g. perfume, mouthwash

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2
Q

What are the effects of 20mg of alcohol per 100mL of blood?

A

Disinhibition- euphoria, emotional, instability and release of social and sexual inhibitions, loss of judgment

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3
Q

What are the effects of 80mg of alcohol per 100mL of blood

A

Above effects become pronounced and motor coordination becomes affected and there is a marked effect on judgement

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4
Q

What are the effects of 200mg of alcohol per 100mL of blood

A

Motor coordination is progressively lost and speech becomes slurred

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5
Q

What are the effects of 300mg of alcohol per 100mL of blood

A

Unconsciousness

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6
Q

What are the effects of 400mg of alcohol per 100mL of blood

A

Death from respiratory failure

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7
Q

What is the highest level of blood alcohol ever seen?

A

628mg/100mL of blood

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8
Q

What is pharmacokinetics of alcohol?

A

Pharmo (drugs) kinetics (movement)- i.e. movement of drugs around the body

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9
Q

Where is alcohol rapidly absorbed?

A

Mouth, lungs, stomach and small intestine

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10
Q

Where is alcohol absorbed if drinking about 20%?

A

Stomach and rest of small intestine (peak blood concentration in 30-60 minutes)

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11
Q

Where is alcohol cleared from?

A

Predominantly by metabolism in the liver

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12
Q

Why does fizzy/gassy alcohol get you drunker quicker?

A

Alcohol is inhaled into the lungs

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13
Q

What causes a hangover?

A

Ethanal

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14
Q

What does alcohol metabolise to?

A

CH3CH2OH + NAD+ -> CH3CHO + NADH

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15
Q

What is clearance of alcohol?

A

Zero order (alcohol clears at a constant rate) i.e. ethanol cleared at a constant rate regardless of concentration

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16
Q

What is an Intoximeter (IR/EC)

A

Detection of alcohol in expired air

Detects mouth alcohol and interfering substances

17
Q

What does an Intoximeter measure?

A

Lung alcohol concentration

18
Q

How is alcohol content in blood measured?

A

Usually gas chromatography of extracted blood sample with IR/EC detector

19
Q

What does IR stand for?

20
Q

What does EC stand for?

A

Electron Capture- specifically picks up alcohol

21
Q

What is the Road Traffic Act 1988 Section 4 (1)?

A

Driving a motor vehicle whilst unfit through drink or drugs

22
Q

What is the Road Traffic Act 1988 Section 4 (2)?

A

Being in charge of a motor vehicle whilst unfit through drink or drugs
Field Impairment test shows nothing about the ability to drive

23
Q

What is the Road Traffic Act 1988 Section 5 (1)(a)?

A

Driving a motor vehicle after consuming so much alcohol that the proportion in breath or blood was >22 microgrammes per 100mL of breath, >50 milligrammes per 100mL of blood or >69 milligrammes of alcohol in 100mL of urine.

24
Q

What is the Road Traffic Act 1988 Section 5 (1)(b)?

A

Being in charge of a motor vehicle after consuming so much alcohol that the proportion in breath or blood was >35 microgrammes per 100mL of breath, >80 milligrammes per 100mL of blood or > 107 milligrammes of alcohol in 100mL of urine.

25
What is the procedure when it comes to drink driving?
Police stop suspect- accident or other road traffic offence Detect alcohol (smell) Roadside breath test If positive, arrest and take to Police Office Intoximeter procedure
26
If the intoximeter is <40 what do you do?
Release without charge
27
If the intoximeter is >50 what do you do?
Charge
28
If the intoximeter is between 40-50 what do you do?
Take blood/urine sample
29
What is statutory defence?
In which a party cannot be shown to have acted purposely, knowingly, recklessly, or negligently as the law may require, with respect to each material element of the offence.
30
What is a statutory defence in drink drive cases?
No intention to drive need calculation of when subject would fall below the statutory limit
31
What are the lines of defence in drink driving cases?
Section 4 & 5- statutory defence | Post-incidence drinking
32
How can post-incidence drinking be a defence?
Drink after the events been occurred | E.g. Have hip flask in car, be pulled over and then take a drink before the police speak to you
33
How can section 5 be used as a defence?
Spiked drinks Calculations required to verify evidence How are calculations done
34
How are calculations of alcohol concentration calculated?
Height and weight of subject Amount of alcohol consumed (type and volume) When alcohol consumed (important is START TIME) Intoximeter and/or blood sample readings What times values needed for
35
What is the difference in gender between uptake and clearance of alcohol?
There is no difference between males and females