Alcohol Flashcards
What is ethanol?
CH3CH2OH, alcohol
Colourless, volatile liquid
Also found in many other products e.g. perfume, mouthwash
What are the effects of 20mg of alcohol per 100mL of blood?
Disinhibition- euphoria, emotional, instability and release of social and sexual inhibitions, loss of judgment
What are the effects of 80mg of alcohol per 100mL of blood
Above effects become pronounced and motor coordination becomes affected and there is a marked effect on judgement
What are the effects of 200mg of alcohol per 100mL of blood
Motor coordination is progressively lost and speech becomes slurred
What are the effects of 300mg of alcohol per 100mL of blood
Unconsciousness
What are the effects of 400mg of alcohol per 100mL of blood
Death from respiratory failure
What is the highest level of blood alcohol ever seen?
628mg/100mL of blood
What is pharmacokinetics of alcohol?
Pharmo (drugs) kinetics (movement)- i.e. movement of drugs around the body
Where is alcohol rapidly absorbed?
Mouth, lungs, stomach and small intestine
Where is alcohol absorbed if drinking about 20%?
Stomach and rest of small intestine (peak blood concentration in 30-60 minutes)
Where is alcohol cleared from?
Predominantly by metabolism in the liver
Why does fizzy/gassy alcohol get you drunker quicker?
Alcohol is inhaled into the lungs
What causes a hangover?
Ethanal
What does alcohol metabolise to?
CH3CH2OH + NAD+ -> CH3CHO + NADH
What is clearance of alcohol?
Zero order (alcohol clears at a constant rate) i.e. ethanol cleared at a constant rate regardless of concentration