Alcohol Flashcards

1
Q

how is alcohol metabolised

A

distributed through body water
concentration in liver is greater as blood comes directly from stomach to liver via portal vein

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2
Q

how is alcohol absorbed

A

slowly absorbed in the stomach
quicker absorption in small intestine

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3
Q

how much alcohol is metabolised in liver

A

90%

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4
Q

what affects blood alcohol concentration

A

age
sex
size
body build
previous exposure
type of alcohol
whether food is taken

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5
Q

when does alcohol peak in blood

A

an hour after drinking

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6
Q

what does alcohol stimulate

A

dopamine and serotonin

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7
Q

what is the drink driving limit in scotland

A

50 mg per 100ml

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8
Q

why might people die from alcohol in blood being over 400mg per 100 ml

A

atrial fibrillation
respiratory failure
inhalation of vomit

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9
Q

what is the safe level of alcohol consumption a week

A

14 units

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10
Q

what health effects can alcohol have on the blood

A

macrocytosis
thrombocytopenia
leucopoenia

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11
Q

what are oral problems associated with heavy drinking

A

oral ulceration
angular cheilitis
dental neglect and trauma
lost dentures
salivary gland enlargement
xerostomia

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12
Q

why can poor wound healing and osteomyelitis occur during heavy alcohol consumption

A

suppression of immune system by alcohol

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13
Q

what is cirrhosis

A

healthy liver tissue replaced with scarred tissue

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14
Q

what is the most common causeof liver cirrhosis

A

alcohol

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15
Q

what are the problems with liver disease for dentists

A

reduced synthesis of clotting factors
combined reduced resorption of Vit K
thrombocytopenia
megakaryocyte maturation reduced gives lower platelets
platelet aggregation reduced

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16
Q

why might thrombocytopenia occur in liver disease

A

splenomegaly associated with portal hypertension
megakaryocyte maturation reduced leading to fewer platelets

17
Q

why might there be an increase in LA and antibiotic metabolism in patients with liver damage

A

heavy drinking induces liver enzymes

18
Q

what is the disulfiram reaction

A

inhibits alcohol dehydrogenase which converts acetaldehyde to acetate causing acetaldehyde to build up and cause nausea and vomiting
used to treat alcoholism

19
Q

what drugs in dentistry can cause disulfiram reaction

A

metronidazole

20
Q

why must you avoid aspirin and NSAIDs in patients with liver damage

A

GI bleeding

21
Q

why should patients with Hep C abstain from alcohol

A

can cause liver disease very easily

22
Q

what occurs taking alcohol and cocaine together

A

new chemical is produced which is similar to cocaine but with longer half life

23
Q

what occurs taking cannabis and alcohol together

A

absorption of alcohol reduced but combination increases sensation of confusion

24
Q

what cardiovascular diseases are associated with alcohol

A

cardiomyopathy
cardiac arrhythmias

25
what is cardiomyopathy
degenerative heart disease with no coronary artery disease
26
what cardiac arrhythmias can alcohol induce
atrial fibrillation prolonged Q-T intervals inverted T waves heart block ventricular arrhythmias
27
what is a protective effect of alcohol
low consumption reduces incidence of coronary artery disease
28
what two conditions does alcohol have a protective effect over other than coronary artery disease
gallstones macular degeneration
29
what are side effects from oral cancer surgery
permanent disfigurement problems with speech problems with eating
30
how does alcohol play a role in oral cancer
acetaldehyde promotes tobacco initiated tumours and facilitates absorption of carcinogenic substances across the oral mucosa
31
what are dental trauma effects of alcohol
broken teeth lost teeth damage to soft tissues lost dentures
32
what are dental tissue side effects of alcohol
non-carious tooth surface loss as alcohol is very acidic vomiting bruxism
33
what is hazardous drinking
risks for problems are likely
34
what is harmful drinking
problems associated with alcohol are actually present
35
what is dependent drinking
alcohol is needed to function
36
what two types of drinking are amendable to brief intervention
hazardous and harmful
37
what is the FRAMES acronym for brief motivational intervention
feedback to patient responsibility with patient advice to change menu of self-directed change treatment empathy self-efficacy