Alcohol Flashcards

1
Q

What steps helped to reduce the amount of alcoho, consumed in Scotland (precovid)?

A

Minimum pricing- 2018 it was inplemented.
Regulation of the market
Reduction in avalibility

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2
Q

Who was most harmed by the excess drinking in Scotland?

A

Older men who drank at home

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3
Q

What are the possible effects of alcohol?

A

Low doses- euphoria, reduced anxiety, relaxation, sociability

Higher doses- intoxicaton, imparied judgement and attention, unsteadiness, flushing, nystamus, mood instability, disinhibition, slurring, stupor and unconsiousness.

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4
Q

What are the potential alcohol diagnosis?

A

Acute intoxication
Harmful used
Dependance
Withdrawal state.

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5
Q

Define harful use

A

Harmful Use – pattern of use causing damage to physical or mental health. Use >1 month or repeatedly over 12 months

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6
Q

Define Dependance

A

3 or more of the following for >1month or repeatedly over 12 months:

Cravings/compulsions to take

Difficulty controlling use

Primacy- neglecting other things/interests

Increased tolerance- need to increase amount of alcohol comsumed to maintain effect

Physiological withdrawal on reduction/cessation

Persistence despite harmful consequences

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7
Q

Define withdrawal state

A

Withdrawal State – Group of symptoms of variable clustering and severity on complete/relative withdrawal of a psychoactive substance, after persistent use of that substance

Symptoms:
Tremor
Weakness
nausea
vomiting
anxiety
seizures
confusion
agitation
death
Delirium tremens
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8
Q

What is deliruim tremens?

A

Profound confusuion, tremor, hallucinations, delusions, sleeplessness, autonomic over-activity

Mortatility in 5% of cases

Death can be caused by cardiovascular collapse, infection, hyperthermia, seizures or self injury

Usually occurs 48-72hrs after alcohol stops

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9
Q

What is Wernicke’s Encephalopathy?

A

Caused by vit B1 deficiency caused by alcohol abuse

Symptoms:
Confusion
Ataxia- disorder of coordination, speech and balance
Opthalmoplegia-a paralysis or weakness of one or more of the muscles that control eye movement.
Nystagmus

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10
Q

What is Korsakoff’s Psychosis?

A

Caused by thiamine deficiency, due to the poor intake and absorption, poor hepatic function, increased requirement for alcohol metabolism

Prominent impairment of recent and remote memory
Preservation of immediate recall
No general cognitive impairment
Retrograde (events that occurred or information that was learned in the past) and anterograde (ability to learn and remember new information, events and facts) memory
impaired learning
disorientation
nystagmus
ataxia
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11
Q

What are the screening tools used for an alcohol problem?

A

CAGE
AUDIT- alcohol use disorders identification test
FAST
PAT- Paddington alcohol test used in A&E’s

TWEAK screening test is the best one for pregnant women

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12
Q

What are the questions in the CAGE screening tool?

A

Have you tried to Cut down?

Have you felt Annoyed by people criticising your drinking?

Have you felt Guilty about drinking?

Have you felt the need to have an Eye-opener?

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13
Q

How do you manage an alcohol problem non-pharmalogically?

A
Education
Support patient and family
CBT, group therapy
Social work input for benefits, housing, child protection if needed
skills training
community/third sector support e.g. AA
Inpatient or residential treatment
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14
Q

WHat are the pharamacolgical treaments for alcohol problem?

A

Thiamine- to prevent Wernicke- Korsakoff

Benzodiazepines- e.g. Chlordiazepoxide for withdrawal

DIsulfiram - aversion/deterent, interacts with any alcohol in food, drink, perfume ect to cause the patient unplesent reactions e.g. vomiting, whole body flushing ect

Anti-craving medication

  • acamprostate
  • naltrexone
  • Nalmefene
  • Baclofen
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15
Q

What are benzodiazepines used for?

A

Usually chlordiazepoxide, used to manage/reduce withdrawal symptoms

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16
Q

What is disulfiram used for?

A

It is an aversion/deterrent medication.
It interacts with any alcohol, in food, drink, perfume ect to cause a horrible reaction such a vomiting, whole body flushing ect to deter the patient from using any alcohol

17
Q

What are naltrexone and nalmefene used for?

A

They are anti-craving medications.

18
Q

What are the criteria for Acute alcoholic hepatitis?

A

Alcohol intake > 6u / day

Jaundice with Bilirubin > 80mg/dl

No other aetiology for Liver inflammation

This has a very high mortality and there is no specific treatment