Aging Skin Flashcards
What is piebaldism?
defective melanocyte mutation. Patches of depigmentation
What is Waardenberg Syndrome?
defective survival of melanocytes. Patches o depigmentation. Enteric ganglion cells affected.
What is Hermansky Pudlak and Chediak Higashi Syndrome?
Ineffective transfer of melanosomes to keratinocytes lead to pigmentary dilution (Silver hair). May also affect neutros, neurons and platelets (traffiking cells)
What is albinism?
Ineffective production of melanin. Melanocytes present, but no melanin.
What layers is the dermis derived from?
ecto and mesoderm
What are the two gastrulation divisions of ectoderm?
ectoderm and neuroectoderm (nerual crest and nerual tube)
What are the five layers of the ectoderm?
stratum corneum, lucidum, spinulosum, basale
What is the vernix caseosa?
protective membrane present at birth. Composed of epithelial cells, sebacious secretions and shed lanugo hair.
What is cutis marmorata?
mottling associated with cold in children/infants. Resolves with re-warming
What is erythema toxicum neonatorum?
a benign skin condition in half of infants. Blotchy red spots on skin with overlying pustules. Resolves spontaneously
What is miliaria?
occlusion of eccrine glands at different levels. Can be crystallina or rubra.
What are phases of atopic dermatitis?
infantile phase- cheeks, forehead, scalp and extensor surfaces (no diaper area)
Childhood phase - flexor surfaces, wrists, ankles, neck, lichenification
Which acne has systemic symptoms?
acne fulminans. Includes fever, arthralgias, osteolytic bone lesions and hepatosplenomegaly
Which severe acne does not hav esystemic symptoms?
acne conglobata
What is acne excoriee de jeunes filles?
acne caused by excessive picking of face
