Aging musculoskeletal Flashcards
sarcopenia
age related loss of skeletal muscle mass and function
Decreased protein reserves
Challenge to meet protein synthesis demands with injury or disease
Normal aging and muscle
Type two atrophy is greater than type one atrophy
Muscle fiber denervation
muscle is 50% total body weight and young adults and is reduced to 25% by age 75
reduce numbers of motor unit activation
Decreased muscle activation
Decreased excitability of spinal and cortical tissues
Muscle metabolic changes
Decreased resting, metabolic rate
Less lean muscle mass
Insulin resistance
Due to increase body fat
(insulin- regulator of protein metabolism)
decreased growth hormone
Decreased estrogen and testosterone
Vitamin D deficiency
Decreased satellite cells
Bone density decreases after age
50
Aging and the skeleton
increased osteoclastic activity
Decreased osteoplastic activity
Osteopenia leads to osteoporosis
osteopenia
Decreased joint load absorption
Decreased load dispersion to all portions of the joint
Increased focal bone loading and increased risk of fracture
joint and normal aging
Decreased activity of osteoblast and chondroblasts
Increased activity of osteoclasts and chondroclasts
decrease response to growth factors
Altered response to tissue loading
connective tissue and normal aging
altered homeostasis, decreased regenerative response
Decreased size and activity of tendon stem cells
Decrease in elastic fibers, responsible for pliability and tensile strength
Alterations in ground substance
Fragment of collagen, strands, and decreased rate of turnover
Increased cross-linking between collagen molecules
-Increased stiffness and decreased ability to absorb energy
Cartilage changes with aging
Chondrocyte senescence
Inflammatory environment + senescence= OA
IVD and aging
nucleus has less water and proteoglycan content= more fibrous
annulus Has less tensile strength due to collagen deposition and cross-linking
Decrease disc height- can lead to loading of surrounding structures
common changes and joints
Decreased joint space
Increased laxity
Altered load dispersion
Altered joint forces
Decreased joint range of motion
cervical spine range of motion trends
Global loss of range of motion
Greatest reduction and extension and lateral flexion
thoracic and lumbar spine range of motion, trends
Extension most limited
Little to no change in rotation
hip range of motion, trends
Extension decreases
Results in decreased walking speed
Ankle range of motion, trends
Dorsiflexion decreases