Ageing and Healthcare Flashcards
1
Q
What is the molecular theory of aging?
A
Gene methylation turns off genes. Histone modification and accumulation of DNA
2
Q
What is the cellular theory of aging?
A
Telomere shortening, free radicle damage to DNA and apoptosis
3
Q
Describe the environmental and evolutionary theory for aging?
A
Wear and tear, inability to regenerate damaged tissue. Accumulative UV and ionising radiation damage.
4
Q
What is the holistic approach to medicine?
A
Tries to see the ‘whole person’ so their physical, psychological, social and functioning well being.
5
Q
What is the phenotype model of frailty
A
- Unintentional weight loss,
- Reduced muscle strength,
- Reduced gait speed,
- Self-reported exhaustion,
- Low energy expenditure.
