Ageing and Healthcare

Question 1

What is the molecular theory of aging?

Answer 1

Gene methylation turns off genes. Histone modification and accumulation of DNA

Question 2

What is the cellular theory of aging?

Answer 2

Telomere shortening, free radicle damage to DNA and apoptosis

Question 3

Describe the environmental and evolutionary theory for aging?

Answer 3

Wear and tear, inability to regenerate damaged tissue. Accumulative UV and ionising radiation damage.

Question 4

What is the holistic approach to medicine?

Answer 4

Tries to see the ‘whole person’ so their physical, psychological, social and functioning well being.

Question 5

What is the phenotype model of frailty

Answer 5

• Unintentional weight loss,
• Reduced muscle strength,
• Reduced gait speed,
• Self-reported exhaustion,
• Low energy expenditure.