Ageing

Question 1

Gerentology

Answer 1

the science of aging

Question 2

geriatry

Answer 2

medicine of old age

Question 3

Deteriorating

Answer 3

aging with diseases and functional disturbances

Question 4

normal aging

Answer 4

without significant pathology but with progressive loss of functioning

Question 5

successful ageing

Answer 5

with less or no physiological deterioration and without much pathology

Question 6

Characteristics of ageins

Answer 6

• unidirectional, i.e. the processes are irreversible although their rate may change or may be changed for some extent;
• progressive increase of differentiation, i.e. function and operation of the cells gets progressively further from the stem-cell state as their become more specialized;
• can be divided into periods, i.e. there are characteristics periods within the life-span;
• universal, i.e. is present in all living creatures

Question 7

Life span

Answer 7

chronological age
biological age
subjective age

Question 8

Summarised definition

Answer 8

Aging is a process taking place in, but not, because of time:

• start at the end of the reproductive period and ends by death
• progressive loss of ability to keep homeostasis and defend against external influences.

Question 9

Theories of aging - programmed ageing

Answer 9

aging gene-cascade

Question 10

Progeria

Answer 10

Early aging

• many aging features in young individuals
• not identical with the true aging
• generally DNA level molecular mechanisms

Question 11

Unified theory of aging?

Answer 11

many cooperating mechanisms

• no one single cause
• complex phenomena, interaction of more factors
• there must be some internal signalisation
• may be controlled by central (clock) mechanisms