Afifi Flashcards

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1
Q

injury from conduction block

A

neuropraxia

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2
Q

injury from loss of axonal continuity

A

axonotmesis

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3
Q

injury from loss of nerve trunk continuity

A

neurotmesis

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4
Q

All neurons have one axon and one dendrite EXCEPT

A
  1. Amacrine cell of retina

2. Granule cells of olfactory bulb

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5
Q

example of unipolar cells

A

dorsal root ganglion

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6
Q

example of bipolar neurons

A

cochlear and vestibular peripheral and olfactory and retinal receptor cells

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7
Q

example of multipolar neurons

A

autonomic ganglia

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8
Q

Structure distinctive in shape and abundant composed of membrane- bound ribonucleoprotein (granular endoplasmic reticulum)

A

Nissl bodies

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9
Q

Nissl bodies are absent where

A

axonal hillock

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10
Q

Neurofilaments. are comprised of 68 to 200 kDA subunits of this structure.

A

tubulin

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11
Q

Resistant proteolipid artifact in myelin

A

neurokeratin

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12
Q

Constitutes a barrier preventing certain substances from entry to axons

A

perineurium

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13
Q

T/F large myelinated fibers conduct nerve impulses FASTER than do small unmyelinated axons

A

TRUE

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14
Q

connective tisssue sheath contiguous with the dura mater

A

epineurium

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15
Q

separates and enceompasses groups of axons into fascicles of different sizes

A

perineurium

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16
Q

continuous with the pia-arachnoid

A

perineurium

17
Q

T/F The conduction velocity of axons is directly related to the axon diameter and the thickness of myelin sheath

A

TRUE

18
Q

What channels are found clustered in the nodes of Ranvier?

A

Sodium

19
Q

Aside from the cells that provide myelin, what is the difference between the myelin of the CNS and PNS?

A

In CNS, the internodal distance and the gap of the node of Ranvier are smaller

20
Q

Ratio of Schwann Cell and oligodendorglia to target neuron?

A

1: 1 for Scwhann
1: 3-200 got Oligodendroglia

21
Q

protein known to provide the motive force to drive organelles along microtubules

A

kinesin

22
Q

protein involved in fast retrograge transport

A

dynein

23
Q

T/F There is no slow retrograde transport component?

A

TRUE

24
Q

Peptides that simulates the growth of fibroblasts and smooth muscle fibers

A

Tachykinin

25
Q

Peptide that affects bone mineralization and stimulates the growth of human keratinocytes

A

VIP

26
Q

Distance between nerve and muscle

A

50 micrometers

27
Q

Fast or slow adapting receptors?

transient and changing stimuli

A

Fast

28
Q

Fast or slow adapting receptors?

sustained stimulus

A

Slow

29
Q

Type of receptor that has no spontaneous discharge at rest and are mroe sensitive to vertical displacement?

A

Type I

30
Q

Type of receptor that maintains a more slow regular discharge at rest and are more sensitive to stretch?

A

Type II

31
Q

Slowly adapting type I mechanoreceptors that are distributed in the germinal layer of the epidermis. Important in Braille reading.

A

Merkel’s corpiscles

32
Q

This means degeneration of a neuron is transmitted to the neuron with which it makes a connection

A

Transneuronal degeneration

33
Q

What are the four types of nerve growth factors?

A
  1. NTF
  2. NPF
  3. Matrix-forming precursors
  4. Metabolic and other factors
34
Q

Sunderland’s Classification Type I

A

conduction block

35
Q

Sunderland’s Classification Type II

A

preserved (wallerian degeneration is distal to the nerve lesion)

36
Q

Sunderland’s Classification Type III

A

internal fascicular structur is disorganized

endoneural sheath is discontinuous

37
Q

Sunderland’s Classification Type IV

A

fascicular nerve structure is destroyed

38
Q

Sunderland’s Classification Type V

A

complete loss of continuity

39
Q

Property of forming new channels of communication after an injury

A

neuronal plasticity