AFib

Question 1

warfarin reversal

Answer 1

vitamin k and PCC/Kcentra

Question 2

heparin/enoxaparin reversal

Answer 2

protamine

Question 3

DOAC reversal

Answer 3

Andexanet alfa and PCC/Kcentra

Question 4

when to adjust eliquis afib/stroke dose?

Answer 4

Age ≥80 years
body weight ≤60 kg
serum creatinine ≥1.5 mg/dL

Question 5

BP goal for altaplase

Answer 5

under 185/110 before giving it, maintained at 180/105 after for at least 24hr

Question 6

altaplase contraindicatons

Answer 6

internal bleeding
recent stroke within 3 months
LMWH within 24hr
DOAC/direct thrombin inhibitor within 48 hour
warfarin with INR 1.7

Question 7

alteplace dosing

Answer 7

0.9 mg/kg (actual body weight), maximum dose 90 mg

10% given as IV bolus over one minute, infuse the rest over 60 minutes

Question 8

Tenecteplase dosing

Answer 8

0.25 mg/kg (actual body weight), maximum dose 25 mg

Entire dose given as IV bolus over 5 to 10 seconds

Question 9

for STEMI, PCI is preferred to be preformed within

Answer 9

90 min

Question 10

anticoag

Answer 10

DOAC
warfarin
heparin
enoxaparin

Question 11

antiplatelet

Answer 11

Aspirin
Clopidogrel (Plavix)
Prasugrel (Effient)
Ticagrelor

Question 12

CHAD-VAS

Answer 12

C Congestive heart failure
H Hypertension:
A Age ≥75 year
D Diabetes mellitus
S2 Prior Stroke or TIA or Thromboembolism

V vascular disease
A Age over 65
S - sex (female)

Question 13

eliquis afib dose

Answer 13

5mg BID
reduced: 2.5mg BID

Question 14

xarelto afib dose

Answer 14

20mg daily

Question 15

warfarin factors

Answer 15

factors II (half-life 42 to 72 hours),
VII (half-life 4 to 6 hours),
IX, and X (half-life 27 to 48 hours)