AEDs

Question 1

Drugs which cause constipation

Answer 1

Anti-muscarinics: hyoscine, oxybutynin, tolterodine , TCAs, anti-psychotics
Cations: iron salts, calcium salts, aluminium salts (antacids)
Calcium channel blockers: verapamil
Opioids

Question 2

Drugs which prolong QT interval

Answer 2

Amiodarone
Anti-psychotics
Quinolones
Macrolides
SSRIs
TCAs
Quinine
Haloperidol
Ondansetron

Question 3

What drugs cause hyperkalaemia

Answer 3

ACEI/ARB
Aldosterone antagonists (spirinolactone)
K+ sparing diuretics
KCl fluid

Question 4

Drugs which cause hypokalaemia

Answer 4

Insulin
Salbutamol
Loop diuretics

Question 5

What drugs cause SIASH (low Na)

Answer 5

Carbamazepine
SSRIs
TCAs
Sulfonureas,
Vincristine
Cyclophosamide

Question 6

What drugs can induce urinary retention?

Answer 6

TCAs
Anti-cholinergics
Opioids
NSAIDs
Dispyramide
+

Question 7

What drugs can cause bleeding / PUD

Answer 7

SSRIs
Antiplatelets
NSAIDs
Steroids

Question 8

what can cause hyperglycaemia

Answer 8

Thiazides/ furosemide
Steroids
Tacrolimus, ciclosporin
Interferon-alpha
Nicotinic acid
Antipsychotics

Question 9

What drugs can cause hypoglycaemia

Answer 9

Insulin
Sulphonureas
Alcohol

Question 10

What drugs can cause lung fibrosis

Answer 10

Amiodarone
Cytotoxic agents: busulphan, bleomycin
DMARDs (methotrexates, sulfasalazine)
Nitrofurantoin