Adverse effects of drugs Flashcards

1
Q

Beta Blockers

A
Contra- indicated in asthma 
Can cause; 
bronchospasm 
tiredness
hypotension
heart failure
cold peripheries 
bradycardia
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2
Q

ACE inhibitors

A

Dry cough
Hyperkalaemia
Angioedema
Hypotension

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3
Q

Loop Diuretics

A
Impaired glucose tolerance / hyperglycaemia
Gout 
Hypokalaemia
Hyponatraemia
Arrhythmias
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4
Q

Amlodipine

A

Headache
Flushing
Ankle swelling

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5
Q

Verapamil

A
SHOULD NOT BE GIVEN WITH BETA BLOCKERS
Heart block 
Constipation 
Flushing 
Precipitation of digoxin toxicity 
Ankle Oedema 
Hypotension 
Dizziness
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6
Q

Adenosine

A

Bronchospasm
Lengthening of the QT interval
Chest pain

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7
Q

Digoxin

A
Gynaecomastia 
Bradycardia 
Heart Block
Confusion 
Anorexia 
Yellow-green vision
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8
Q

Amiodarone

A
Hyperthyroidism 
Peripheral Neuropathy 
Photosensitivity 
Hepatotoxicity 
Pulmonary fibrosis 
Precipitation of digoxin toxicity 
Slate- grey appearance
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9
Q

Statins

A

Myalgia / Myopathy / Myositis
Renal Failure
Hepatotoxicity

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10
Q

Thiazides

A

Precipitation of digoxin toxicity

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11
Q

Nitrates

A

Postural Hypotension
Headaches
Flushing

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12
Q

Dilitiazem

A
Heart block 
Precipitation of digoxin toxicity 
Hypotension
Bradycardia
Heart failure 
Ankle swelling
Gingival hyperplasia
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13
Q

Ivabridine

A
Headache 
AF 
1st degree heart block 
Bradycardia
Blurred vision
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14
Q

Hydralazine (a rarely used anti-hypertensive)

A
tachycardia
palpitations
flushing
fluid retention
headache
drug-induced lupus
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15
Q

A patient presents with sudden onset severe pain at the base of the big toe, what drug is this side- effect most likely to have been caused by?

A

Gout - a side effect of thiazide diuretics!

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16
Q

Spironolactone

A

Breast tenderness in men

17
Q

What drug can cause cold peripheries

A

Beta blockers

18
Q

What drug can cause bronchospasm?

A

Adenosine

19
Q

Which drug used in the treatment of arrhythmias can cause hypothyroidism?

A

Amiodarone

20
Q

A patient with Wolff Parkinson White syndrome can be treated with beta blockers. However with what co-morbidity should they not have this treatment?

A

Atrial Fibrillation