Adult I Exam 3 - Endocrine Alterations: Diabetes Mellitus Flashcards

0
Q

Prediabetes

A

Fasting blood glucose 100-125
2hr OGTT 140-199 (oral glucose tolerance test)
A1C 5.7-6.4%

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1
Q

Diabetes Classifications

A
DM Type 1
DM Type 2
Hyperglycemia 
Gestational Diabetes
Metabolic Syndrome
Hyperglycemia
Prediabetes
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2
Q

Alpha cells

A

Glucagon

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3
Q

Beta cells

A

Insulin & amylin

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4
Q

Glucose Homeostasis

A

Balance of glucose uptake & glucose production

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5
Q

S/S high serum glucose

A

Polyuria
Fruit smelling breath
Polydipsia
Poly

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6
Q

Hyperglycemia S/S

A

Polyuria
Polydipsia
Polyphagia
Keytones

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7
Q

DM guidelines - Gold Standards

A

ADA - American Diabetes Association

AACE- American Associations of Clinical Endocrinologist

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8
Q

Primary Prevention of Diabetes

A
Balanced nutrition & physical activity
Weight loss for obese/overweight
Physical activity 150min/week
Diet- low-carb, low-fat, calorie restricted, or Mediterranean 
Screening
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9
Q

How often should diabetes screening be performed?

A

> 45yo &/or BMI >25 at least every 3 years

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10
Q

Diagnosis Criteria for Diabetes

A

Hgb A1C

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11
Q

Fasting Blood Glucose (FBG)

A

No calorie intake for 8 hours

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12
Q

Oral Glucose Tolerance Test (OGTT)

A

Take after 10-12hr fasting
75-100g glucose beverage
2 hours post-load results

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13
Q

Glycosylated hemoglobin (Hgb A1C)

A

Average blood glucose for previous 120 days

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14
Q

Type 1 DM

A

.

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15
Q

Type 2 DM

A

.

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16
Q

Management of Diabetes

17
Q

Blood Glucose Goals

A

Increased glucose usage when ill so ranges vary

18
Q

Purpose/action of Insulin

A

Moves glucose into the cells (stimulates uptake into cell)

Inhibits hepatic glucose production

19
Q

Action of Glucagon

A

Releases glucose from liver & cells

.??

20
Q

Other causes of elevated blood glucose

A

Stress reaction/response

Steroids

21
Q

Rapid Acting Insulin

22
Q

Short Acting Insulin

23
Q

Intermediate-Acting Insulin

24
Long-Acting Insulin
``` Onset = 2-4 hours Peak = NONE Duration = Drug- Teaching- ```
25
Mixed Insulin
Advantages: better control/stability, no mixing needed Disadvantages: get low, stay lower longer, have to adhere to meal & exercise schedule
26
Sliding Scale Insulin (SSI)
.
27
Correction Insulin
.
28
Insulin Pump
.
29
Insulin Administration & storage
.
30
Insulin Verification
.
31
Common Complications of Insulin
.
32
Hypoglycemia S/S
.
33
S/S absence of Insulin
.
34
Chronic Complication - Microvascular
Changes in small blood vessels and organs Nephropathy Neuropathy Retinopathy
35
Chronic Complications - Macrovascular
Changes in large blood vessels
36
Why do rotating insulin injection sites
To prevent: Lipohypertrophy (increase swelling of fat) Lipoatrophy (loss of fat)- leads slower inconsistent absorption
37
Hypoglycemia tx actions
.
38
Risk factors for metabolic syndrome
"apple shape" | Waist circumference...
39
Target goal BP
<130/80 Weight control & increase activity to achieve Initiate ACE inhibitor if goal cannot be met