Adult I Exam 3 - Endocrine Alterations: Diabetes Mellitus Flashcards

0
Q

Prediabetes

A

Fasting blood glucose 100-125
2hr OGTT 140-199 (oral glucose tolerance test)
A1C 5.7-6.4%

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1
Q

Diabetes Classifications

A
DM Type 1
DM Type 2
Hyperglycemia 
Gestational Diabetes
Metabolic Syndrome
Hyperglycemia
Prediabetes
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2
Q

Alpha cells

A

Glucagon

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3
Q

Beta cells

A

Insulin & amylin

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4
Q

Glucose Homeostasis

A

Balance of glucose uptake & glucose production

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5
Q

S/S high serum glucose

A

Polyuria
Fruit smelling breath
Polydipsia
Poly

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6
Q

Hyperglycemia S/S

A

Polyuria
Polydipsia
Polyphagia
Keytones

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7
Q

DM guidelines - Gold Standards

A

ADA - American Diabetes Association

AACE- American Associations of Clinical Endocrinologist

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8
Q

Primary Prevention of Diabetes

A
Balanced nutrition & physical activity
Weight loss for obese/overweight
Physical activity 150min/week
Diet- low-carb, low-fat, calorie restricted, or Mediterranean 
Screening
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9
Q

How often should diabetes screening be performed?

A

> 45yo &/or BMI >25 at least every 3 years

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10
Q

Diagnosis Criteria for Diabetes

A

Hgb A1C

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11
Q

Fasting Blood Glucose (FBG)

A

No calorie intake for 8 hours

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12
Q

Oral Glucose Tolerance Test (OGTT)

A

Take after 10-12hr fasting
75-100g glucose beverage
2 hours post-load results

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13
Q

Glycosylated hemoglobin (Hgb A1C)

A

Average blood glucose for previous 120 days

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14
Q

Type 1 DM

A

.

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15
Q

Type 2 DM

A

.

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16
Q

Management of Diabetes

A

.

17
Q

Blood Glucose Goals

A

Increased glucose usage when ill so ranges vary

18
Q

Purpose/action of Insulin

A

Moves glucose into the cells (stimulates uptake into cell)

Inhibits hepatic glucose production

19
Q

Action of Glucagon

A

Releases glucose from liver & cells

.??

20
Q

Other causes of elevated blood glucose

A

Stress reaction/response

Steroids

21
Q

Rapid Acting Insulin

A

.

22
Q

Short Acting Insulin

A

.

23
Q

Intermediate-Acting Insulin

A

.

24
Q

Long-Acting Insulin

A
Onset = 2-4 hours
Peak = NONE
Duration = 
Drug-
Teaching-
25
Q

Mixed Insulin

A

Advantages: better control/stability, no mixing needed
Disadvantages: get low, stay lower longer, have to adhere to meal & exercise schedule

26
Q

Sliding Scale Insulin (SSI)

A

.

27
Q

Correction Insulin

A

.

28
Q

Insulin Pump

A

.

29
Q

Insulin Administration & storage

A

.

30
Q

Insulin Verification

A

.

31
Q

Common Complications of Insulin

A

.

32
Q

Hypoglycemia S/S

A

.

33
Q

S/S absence of Insulin

A

.

34
Q

Chronic Complication - Microvascular

A

Changes in small blood vessels and organs
Nephropathy
Neuropathy
Retinopathy

35
Q

Chronic Complications - Macrovascular

A

Changes in large blood vessels

36
Q

Why do rotating insulin injection sites

A

To prevent:
Lipohypertrophy (increase swelling of fat)
Lipoatrophy (loss of fat)- leads slower inconsistent absorption

37
Q

Hypoglycemia tx actions

A

.

38
Q

Risk factors for metabolic syndrome

A

“apple shape”

Waist circumference…

39
Q

Target goal BP

A

<130/80
Weight control & increase activity to achieve
Initiate ACE inhibitor if goal cannot be met