ADRs & contraindications Flashcards
If somemone is having like an anaphylactic reaction from a drug, how do you manage
SECURE AIRWAY
then Adrenaline
ABXs ending in …floxacin (e.g. cipro)
Methylphenidate
Buproprion
Alcohol & cocaine
These drugs all do what
Worsen seizure control
What drugs should you avoid in heart failure
NSAIDs
Steroids
Veramapil
Flecanide
Diabetes med -> Pioglitazone
What TB drugs cause these SEs
- orange secretions, hepatitis, flu-like symptoms
- peripheral neuropathy, hepaitits & agranulocytosis
- optic neuropathy
- gout, sore muscles & joints
- rifampicin
- isoniazid
- ethambutol
- pyrazinamide
What TB drug causes optic neurpathy
Ethambutol
Eye = Ethambutol
What ABxs should you avoid in preggers
Gent & Vanc (aminoglycosides)
Co-trimox (sulphonamides)
Trimethoprim (1st trimester)
Ciprofloxacin (quinolones)
Doxycyline (tetracyclines)
Other than ABxs, what drugs should be avoieded in preggers
Statins
Warfarin
ACEi & ARBs
Suplonylureas
Retinoides
Valporate & phenytoin
What would happen if you’re on metroindazole but drink some alcohol
Gonna be seeeeeeek
(disulfarim reaction)
Why should you never give B-blockers & verampail (CCBs) together
High risk of…
Hypotension & Asytole
What drugs are an issue in IHD
NSAIDs
cOCP & HRT
diabeteic indivudal
Low GCS
Signs of lactic acidosis
What drug is probs the cause
Metformin
what drugs would you be worried about a pt being on if they’re getting some contrast for a scan
Metformin
ACEi
What are the common and serious SEs of statins
Common -> myalgia
Serious -> rhabdomylosis
what is apprantley an SE of inhalers
Pneumonia
What are the common and serious SEs of B-Blockers
Common -> fatigue
Serious -> hypotension
What drugs commonly cause these SEs…
- cough
- oedema
- pulmonary firbosis
- low Na
- Agranulocytosis
- Hypoglycemia
- Lactic acidosis & liver damage
- Myalgia
- Constipation & pulomnary fibrosis
- hearing loss
- ACEi
- amoldipine (CCBs)
- methotrexate
- carbamazepine
- cloazepine
- glicazides
- metformin
- statins
- methotrexate
- gent & vanc
what do you do if a pt gets muscle aches from a statin
Stop it
restart once syptoms reslove
What antihypertensives cause the following SEs
- Bradycardia, acute heart failure, fucks asthma
- bradycardia, flushing, periperal oedema
- Fucked kidneys, high K, dry cough
- fucked U&Es, dehydratoin, gout
- fucked U&Es, dehydratoin, gynaecomastia
- b-blockers
- CCBs
- ACEi
- thiazide diuretics
- K-sparring diuretics
what is funny about B-blockers and heart failure
Used 1st line to treat if chroinc
Can cause acute heart failure lol
what drugs can’t you prescribe in heart failure
NSAIDS
Steroids
Flecaninde (used for AF)
TCAs
What drugs are contrainidcated in parkinsons
Metoclopramide
Halopreidol
what to search up in the BNF for hyperkalaemia
Electrolyte imbalance
But some do hava ‘hyperkalmeia’ so search that up too eh
what sorta SEs can you get with oxybutynin
anti-cholingeric
Dry mouth
Constipation
Confusion
what drugs can cause dyspepsia
NSAIDS
steroids
mood changes is an SE of which dryg
steroids
If you find like 2 drugs that cause ‘electrolyte imbalabce’, how can you find the specific imbalance that’s fucked
Look up INTERACTIONS with one of the prescribed meds
Then it might say eh
also check for MONITORING SHITE
what’s one of the commonest SEs of lithium
Restlessness
What main SE does amiodarone have
Hepatotoxic
Will fuck up the liver and raise those enzymes
Is SOB a common SE of ticagrelor?
Yes
can omeprazole cause low sodium?
Yes, yes it can
what are common cause of medication overuse headaches
Codeine
Paracetamol
aspirin
Triptans
what HRT is used to treat hot flushes
what is a SE
Estradiol
Increased risk of VTE
what blood test sign is a sign of a paracetamol OD
Rise in ALT
what ABX has a photosensitivity reaction as an SE
TETRACYCLINES
Doxycycline
what ABX commonly causes hypokalemia
Clartihromycin