ADRs & contraindications Flashcards

1
Q

If somemone is having like an anaphylactic reaction from a drug, how do you manage

A

SECURE AIRWAY

then Adrenaline

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2
Q

ABXs ending in …floxacin (e.g. cipro)

Methylphenidate

Buproprion

Alcohol & cocaine

These drugs all do what

A

Worsen seizure control

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3
Q

What drugs should you avoid in heart failure

A

NSAIDs

Steroids

Veramapil

Flecanide

Diabetes med -> Pioglitazone

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4
Q

What TB drugs cause these SEs

  1. orange secretions, hepatitis, flu-like symptoms
  2. peripheral neuropathy, hepaitits & agranulocytosis
  3. optic neuropathy
  4. gout, sore muscles & joints
A
  1. rifampicin
  2. isoniazid
  3. ethambutol
  4. pyrazinamide
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5
Q

What TB drug causes optic neurpathy

A

Ethambutol

Eye = Ethambutol

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6
Q

What ABxs should you avoid in preggers

A

Gent & Vanc (aminoglycosides)

Co-trimox (sulphonamides)

Trimethoprim (1st trimester)

Ciprofloxacin (quinolones)

Doxycyline (tetracyclines)

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7
Q

Other than ABxs, what drugs should be avoieded in preggers

A

Statins

Warfarin

ACEi & ARBs

Suplonylureas

Retinoides

Valporate & phenytoin

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8
Q

What would happen if you’re on metroindazole but drink some alcohol

A

Gonna be seeeeeeek

(disulfarim reaction)

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9
Q

Why should you never give B-blockers & verampail (CCBs) together

A

High risk of…

Hypotension & Asytole

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10
Q

What drugs are an issue in IHD

A

NSAIDs

cOCP & HRT

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11
Q

diabeteic indivudal

Low GCS

Signs of lactic acidosis

What drug is probs the cause

A

Metformin

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12
Q

what drugs would you be worried about a pt being on if they’re getting some contrast for a scan

A

Metformin

ACEi

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13
Q
A
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14
Q

What are the common and serious SEs of statins

A

Common -> myalgia

Serious -> rhabdomylosis

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15
Q

what is apprantley an SE of inhalers

A

Pneumonia

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16
Q

What are the common and serious SEs of B-Blockers

A

Common -> fatigue

Serious -> hypotension

17
Q

What drugs commonly cause these SEs…

  1. cough
  2. oedema
  3. pulmonary firbosis
  4. low Na
  5. Agranulocytosis
  6. Hypoglycemia
  7. Lactic acidosis & liver damage
  8. Myalgia
  9. Constipation & pulomnary fibrosis
  10. hearing loss
A
  1. ACEi
  2. amoldipine (CCBs)
  3. methotrexate
  4. carbamazepine
  5. cloazepine
  6. glicazides
  7. metformin
  8. statins
  9. methotrexate
  10. gent & vanc
18
Q

what do you do if a pt gets muscle aches from a statin

A

Stop it

restart once syptoms reslove

19
Q

What antihypertensives cause the following SEs

  1. Bradycardia, acute heart failure, fucks asthma
  2. bradycardia, flushing, periperal oedema
  3. Fucked kidneys, high K, dry cough
  4. fucked U&Es, dehydratoin, gout
    1. fucked U&Es, dehydratoin, gynaecomastia
A
  1. b-blockers
  2. CCBs
  3. ACEi
  4. thiazide diuretics
  5. K-sparring diuretics
20
Q

what is funny about B-blockers and heart failure

A

Used 1st line to treat if chroinc

Can cause acute heart failure lol

21
Q

what drugs can’t you prescribe in heart failure

A

NSAIDS

Steroids

Flecaninde (used for AF)

TCAs

22
Q

What drugs are contrainidcated in parkinsons

A

Metoclopramide

Halopreidol

23
Q

what to search up in the BNF for hyperkalaemia

A

Electrolyte imbalance

But some do hava ‘hyperkalmeia’ so search that up too eh

24
Q

what sorta SEs can you get with oxybutynin

A

anti-cholingeric

Dry mouth

Constipation

Confusion

25
Q

what drugs can cause dyspepsia

A

NSAIDS

steroids

26
Q

mood changes is an SE of which dryg

A

steroids

27
Q

If you find like 2 drugs that cause ‘electrolyte imbalabce’, how can you find the specific imbalance that’s fucked

A

Look up INTERACTIONS with one of the prescribed meds

Then it might say eh

also check for MONITORING SHITE

28
Q

what’s one of the commonest SEs of lithium

A

Restlessness

29
Q

What main SE does amiodarone have

A

Hepatotoxic

Will fuck up the liver and raise those enzymes

30
Q

Is SOB a common SE of ticagrelor?

A

Yes

31
Q

can omeprazole cause low sodium?

A

Yes, yes it can

32
Q

what are common cause of medication overuse headaches

A

Codeine

Paracetamol

aspirin

Triptans

33
Q

what HRT is used to treat hot flushes

what is a SE

A

Estradiol

Increased risk of VTE

34
Q

what blood test sign is a sign of a paracetamol OD

A

Rise in ALT

35
Q

what ABX has a photosensitivity reaction as an SE

A

TETRACYCLINES

Doxycycline

36
Q

what ABX commonly causes hypokalemia

A

Clartihromycin

37
Q
A