Adrenergic Transmisson

Question 1

Phenylephrine

Answer 1

A1 agonist for acute BP drop(oral) and orthostatic hypotension. Induces bradycardia

Question 2

Dopamine
IBOPAMINE
DOBUTAMINE
What are they?

Answer 2

B1 agonists.

Question 3

Clonidine

Answer 3

A2 agonist totreat high blood pressure. PRESYNAPTİC TERMİNAL BINDING, clonidine withdrawal syndrome

Question 4

Salbutamol

Answer 4

B2 agonist for asthma therapy bronchodilation

Question 5

Atosiban

Answer 5

B2 agonist for premature uterine contractions

Question 6

Exogeneous adrenaline

Answer 6

Preferential Alpha receptor effect, Causes high BP, and bradycardia(lower than phenylephrine)

Question 7

ISOPRENALINE

Answer 7

Diastolic BP decrease, tachychardia

Question 8

Adrenaline (IV)

Answer 8

Low concentration B effect= tachychardia
High concentration A and B effect= less tachycardia

Question 9

Amfetamines

Answer 9

Indirect agonists, stimulates release of NA, dopamine, 5HT

Question 10

EFEDRINE

Answer 10

Indirect agonist, taken up by uptake 1

Question 11

Cocaine

Answer 11

Uptake 1 inhibiting indirect agonist

Question 12

TCA

Answer 12

MAO inhibitor, indirect agonist

Question 13

Labetalol

Answer 13

Bigger A1 and smaller B1 alpha blocker effect

Question 14

Fenoxybenzamine

Answer 14

Irreversible a1 and a2 blocking

Question 15

Pindolol

Answer 15

B blocker with ISO

Question 16

Acebutolol

Answer 16

B blocker with ISO

Question 17

Atenolol

Answer 17

Selective B1 blocker

Question 18

Metaprolol

Answer 18

Selective b1 blocker

Question 19

Acebutolol

Answer 19

Selective b1 blocker

Question 20

Propranolol

Answer 20

Non selective b blocker

Question 21

Timololol

Answer 21

Non selective b1 blocker