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Pharmacology > Adrenergic drugs > Flashcards

Adrenergic drugs Flashcards

1
Q

An alpha and beta agonist used as a DOC for anaphylactic shock, cardiac arrest, and partnered with local anesthetics. It also has more beta-receptor activity

A

Epinephrine

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2
Q

An alpha and beta agonist used as a drug of choice for septic shock. It has more alpha activity, resulting to greater vasoconstriction than epinephrine

A

Norepinephrine

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3
Q

An alpha and beta agonist. At high doses, it has alpha activity. At moderate doses, it has beta activity. At low doses, it has dopaminergic activity

A

Dopamine

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4
Q

An alpha-1 agonist that is used as a nasal decongestant, shock, and mydriatic. It has a side effect of rhinitis medicamentosa, which is why it is suggested that this drug should be taken not more than 3 days

A

Phenylephrine

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5
Q

Alpha-1 agonists used as nasal decongestant

A

Phenylpropanolamine
Pseudoephedrine

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6
Q

An alpha-1 agonist used as treatment for hypotension

A

Methoxamine

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7
Q

Alpha-2 agonists used as treatment for hypertension

One drug is hepatotoxic and is positive for Coomb’s test

One of the alpha-2 agonist used for hypertensive urgency

A

Clonidine, Methyldopa, Guanfacine, Guanabenz

Methyldopa

Clonidine

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8
Q

An alpha-1 and -2 agonist used as an OTC nasal spray decongestant

A

Oxymetazoline

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9
Q

A beta-1 agonist used as a DOC for cardiogenic shock

A

Dobutamine

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10
Q

Beta-2 agonists used for asthma

A

SABA: Albuterol/ Salbutamol, Terbutaline, Metaproterenol
LABA: Salmeterol, Formoterol

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11
Q

A beta-2 agonist that has an off-label indication, which is for premature labor, acting as a tocolytic

A

Terbutaline

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12
Q

A beta- 1 and -2 agonist used for cardiac arrest, but used rarely for asthma

A

Isoproterenol

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13
Q

An indirect acting agonist found in red wine, beer, cheese, and chocolates. It can cause hypertension in patients taking MAO inhibitors, resulting in the “cheese effect”

A

Tyramine

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14
Q

Indirect acting agonists used for ADHD, anorexiant, and management for narcolepsy

A

Methylphenidate
Amphetamine
Phentermine

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15
Q

A mixed direct and indirect agonist which is an alkaloid, coming from Ma Huang (Ephedra sinica). It is used for urinary incontinence, bronchospasm, hypotension, nasal congestion, and narcolepsy

A

Ephedrine

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16
Q

A mixed direct and indirect acting agonist that is used for hypotension

A

Metaraminol

17
Q

Alpha-1 antagonists used for HTN and BPH. However, it has a side effect of orthostatic hypotension due to the first dose. A remedy for this side effect is to adjust the first dose to 1/3 or 1/4 of normal dose

A

Tamsulosin
Doxazosin
Prazosin
Terazosin

18
Q

An alpha-2 antagonist that is used for impotence as penile injection

A

Yohimbine

19
Q

An alpha-1 and -2 antagonist that is irreversible and long-acting for treatment of hypertension caused by pheochromocytoma, which is a tumor in the adrenal medulla, and also for Raynaud disease

A

Phenoxybenzamine

20
Q

An alpha-1 and -2 antagonist that is reversible and short-acting for treatment of hypertension caused by pheochromocytoma, which is a tumor in the adrenal medulla

A

Phentolamine

21
Q

It is a nonselective beta antagonist used for HTN, post-MI, angina pectoris, SVT, and heart failure, known for having the longest half-life among all beta blockers

A

Nadolol

22
Q

It is a nonselective beta antagonist used for HTN, post-MI, angina pectoris, SVT, and heart failure

A

Sotalol

23
Q

It is a nonselective beta antagonist used for HTN, post-MI, angina pectoris, SVT, and heart failure. Aside from these indications, it is also used for treating glaucoma

A

Timolol

24
Q

It is a nonselective beta antagonist used for HTN, post-MI, angina pectoris, SVT, and heart failure that is known to be the prototype for beta adrenergic antagonist. It is has an off-label use for migraine, stage fright, and hyperthyroidism

A

Propranolol

25
Q

They are selective beta-1 antagonists that are indicated for hypertensive patients with impaired pulmonary function

This is the most cardio-selective of all selective beta-1 antagonists

The beta-blocker with the shortest half-life

A

Celiprolol, Nebivolol, Bisoprolol, Betaxolol, Esmolol, Acebutolol, Atenolol, Metoprolol

Nebivolol

Esmolol

26
Q

They are partial beta agonists with intrinsic sympathetic activity, which allows lessening of risks of hypotension and bradycardia

A

Acebutolol
Celiprolol
Penbutolol
Pindolol
Labetalol
Carteolol

27
Q

They are combined alpha and beta antagonists used for hypertensive patients with increased peripheral vascular resistance due to alpha blockade

One of the combined antagonists used for pregnancy-induced hypertension. This drug is also used for hypertensive emergency

A

Labetalol
Carvedilol

Labetalol

28
Q

A drug used to inhibit NE synthesis by inhibiting the formation of L-DOPA through the inhibition of tyrosine hydroxylase

A

Metyrosine

29
Q

A drug used to inhibit the dopamine storage or acts as a VMAT blocker

A

Reserpine

30
Q

These are drugs used to inhibit NE release

A

Guanethidine
Guanadrel
Bretylium

31
Q

These are drugs used to inhibit the NE reuptake for indications that have problems regarding inadequate NE

A

Cocaine
TCAs
Reboxetine

Pharmacology (13 decks)

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