Adrenergic Antagonists Flashcards by Jennifer Bello

Q

Phentolamine

A

A1 and A2 blocker
Treats hypertension caused by pheochromocytoma
Used to reverse local anesthesia with vasoconstrictor

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Q

Tamsulosin

A

A1 blocker
Treatment of enlarged prostate gland
SE: nasal congestion, headache, ortho hypotension

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Q

Propanolol

A

B1 and B2 blocker
Penetrates BBB and treats migraines
SE: bronchoconstriction
(not good for ppl w/ COPD, asthma)

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Q

Metoprolol

A

B1 blocker (blocking B2 = bronchoconstriction)
Treats high BP, chest pain, arrhythmia, heart attack
SE: hypotension, dizziness, increase [glucose] and [lipid]

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Q

Carvedilol

A

Non-selective B antagonist

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Q

Nebivolol

A

B1 blocker

- Increases NO levels (to dilate blood v.v.)

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Q

Carvedilol and Nebivolol advantage?

A

There isn’t increase in [glucose] and [lipid], so it’s diabetic friendly.
Have antioxidant properties which is good for treating heart failure
More effective at treating hypertension

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