Adrenergic Agonists- Trachte Flashcards
What is the equation for BP?
BP = HR X SV X TPR
What do B1 agonist’s do?
Increase BP by…
Increasing HR and SV
What do Alpha1 agonists do?
Increase BP by…
Increasing TPR/ vasoconstriction of vasculature
What do B2 agonists do?
Decrease BP by….
Vasodilating
Phenylephrine
Alpha 1 agonist
Amphetamine
Tyramine
Ephedrine
Reverses the axoplasmic catecholamine transporter
Causes NE release (mimics sympathetic activation)
**Note, doesn’t work in presence of cocaine
Reserpine
inhibits granular pump accumulating catecholamines in vesicles
Pargyline
MAO inhibitor
Potentiates sympathetic response
Cocaine
Inhibits axoplasmic catecholamine transporter
Increases sympathetic response
Albuterol
Metaproterenol
Terbutaline
Activates B2 receptors
Dobutamine
activates B1 receptors
Positive iontrope
Selective for B1
Isoproterenol
Activates B1 and B2
Terazosin
Alpha 1 blocker
Propanolol
non-specific
Blocks Beta 1 and 2
Metoprolol
Specifically blocks Beta 1 receptors