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Pharmakologie > Adrenerges System > Flashcards

Adrenerges System Flashcards

1
Q

Alpha 1 Agonisten

A

Imidazole: Oxymetazolin (Nase), Naphazolin (Auge), Xylometazolin (Nase, Auge)
Phenynephrin (Auge)

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2
Q

Noradrenalin

A 
Alpha > Beta 1 > Beta 2
RR hoch (Alpha)
HF runter (durch erhöhten Widerstand Barorezeptoren aktiviert, drosseln die HF)
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3
Q

Adrenalin

A

Beta 1, Beta 2 > Alpha
Vasodilatation, HF, Kontraktilitat usw hoch
Hohe Dosen: Vasokonstriktion über Alpha

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4
Q

Isoprenalin (Orciprenalin)

A

Beta 1 = Beta 2
Vasodilatation
HF usw hoch

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5
Q

Dopamin

A 
D1 > Beta 1 > Alpha
D1 in Mesenterial-& Renalgefäßen Vasodilatation 
Beta 1 HF usw hoch
Alpha Vasokonstriktion 
Wirkungen dosisabhängig
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6
Q

Dobutamin

A

Beta 1 > Alpha = Beta 2

α = β2: Vasokonstriktion und –dilatation in Waage → keine Gefäßwirkungen β1: Herz: HF↑, Kontraktilität↑, HZV↑

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7
Q

Beta 2 Mimetika

A

Terole
Oral: Tuloterol, Bambuterol, Clenbuterol, Fenoterol (Wehenhemmung)
Inhalativ: Formoterol, Reproterol, Salbutamol, Salmeterol, Terbutalin

Bei Asthma bronchiale, Wehenhmmung (Tokolyse)

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8
Q

Indirekte Sympathomimetika

A

Hemmung der Wiederaufnahme, vermehrte Freisetzung von Monoaminen

Tyramin (Rotwein, Käse)
Ephedrin (Erkältungssaft)
Amphetaminderivate, Kokain
Methylphenidat (ADHS, Narkolepsie)
Atomoxetin (ADHS)
Modafinil (Narkolepsie)
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9
Q

Alpha Blocker

A

α1&raquo_space; α2: Doxazosin, Prazosin, Terazosin, Indoramin (arterielle Hypertonie: Mittel 2. Wahl)
α1A (Prostata, Urethra: Urologika): Tamsulosin, Alfuzosin (Prostatahyperplasie)
α1 = α2: (Phentolamin), Phenoxybenzamin (Phäochromozytom)
α1

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10
Q

Beta Blocker

A

Nicht selektiv: Propanolol, Carvedilol, Sotalol, Timolol,Pindolol
Beta 1: Atenolol, Bisoprolol, Esmolol, Metoprolol, Celiprolol
Vasodilatation: Carvedilol (Alpha), Nebivolol (NO)

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11
Q

Antisympathotonika

A

Senken den Sympathikustonus
Reserpin (MAO Transport Hemmung - keine Wiederherstellung von NA)
Guanethidin (Na Kanal Hemmer)
Clonidin, Moxonidin (Alpha 2 Aktivierung - NA Ausschüttung gehemmt)
Alpha Methyl Dopa (Alpha 2 Aktivierung)

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Pharmakologie (3 decks)

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