Adrenerge Pharmaka Flashcards

1
Q

Adrenalin

A

Agonist
alpha1-beta3 adrenerg

HORMON

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2
Q

Noradrenalin

A

Agonist
alpha1-beta1 adrenerg, beta3 adrenerg

NEUROTRANSMITTER

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3
Q

Phenylephrin

A

Agonist

alpha1 adrenerg

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4
Q

Clonidin

A

Agonist
alpha2 adrenerg -> hemmt Symphatikotonus
NE: Sedierung, Bradykardie, Hypotonie, Mundtrockenheit

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5
Q

Moxonidin

A

Agonist

alpha2 adrenerg bei Hypertonie, weniger sedierend als Clonidin

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6
Q

Dexmedetomidin

A

Agonist

alpha2 adrenerg zur Sedierung

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7
Q

Xylometazolin

A

Agonist

alpha2 adrenerg

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8
Q

Fenoterol, Salbutamol, Salmeterol, Formoterol

A

Agonist (Beta2-Mimetika)
beta2 adrenerg
Salbutamol, Terbutalin, Fenoterol -> 4-6h Wirkdauer
Formoterol, Salmeterol -> 12h Wirkdauer, langsamer Eintritt
NE: Tachykardie, Tremor, Hyperglykämie bei Diabetes, Hypokaliämie
TH: Bronchodilatation, kurzfristige Senkung des Plasma-K, Togolese

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9
Q

Mirabegron

A
Agonist
beta3 adrenerg
CYP3A4, hemmt p-Glykoprotein
KI bei starken CYP Induktoren (z.B: Clarithromycin)
relaxiert Harnblasenmuskulatur,
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10
Q

Doxazosin

A

Antagonist

alpha1 adrenerg

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11
Q

Tamsulosin

A

Antagonist

alpha1 adrenerg

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12
Q

Mirtazapin

A

Antagonist

alpha2 adrenerg

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13
Q

Metoprolol

A

Antagonist

beta1 adrenerg

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14
Q

Bisoprolol

A

Antagonist

beta1 adrenerg

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15
Q

Propranolol

A

Antagonist

beta1-2 adrenerg

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16
Q

alpha-Methyldopa

A

Agonist
wird im Organismus zu alpha-Methyl-NA umgewandelt
hemmt Dopa-Decarboxylase -> Verminderte NA-Synthese
alpha-Methyl-NA stimuliert alpha2-Rezept.
nur noch bei Hypertonie in Schwangerschaft