adrenal glands Flashcards
what is Addison disease?
decreased production of cortisol
gluceogenesis decreases, with resultant hypoglycemia and liver glycogen deficiency
what hormones do the cortex produce?
mineralcorticoids
glucocorticoids
sex hormone
what symptoms would a person with Addison disease show?
grows weak, exhausted, hypotensive, and suffers from anorexia, weight loss, nasea, and vomiting
what hormones do the medulla secrete?
epinephrine
norepinephrine
what other hormones increase in response to Addison disease?
increase in ACTH
MSH
what does a person with Addison’s disease and increase MSH look like?
excessive MSH increases skin and mucous membrane pigmentation
what are some PT implications for Addison’s disease?
stress should be minimized
aquatic therapy is contraindicated
watch for impending crisis
primary adrenal insufficiency is also related to what other deficiencies?
aldosterone
decreased serum cortisol levels
true or false: secondary adrenal insufficiency is related to cortisol deficiency ONLY
true
what is Cushing syndrome?
glucocorticoid excess
what is Conn syndrome or aldosteronism?
aldosterone excess
what disease is hypercortisolism associated with?
Cushing syndrome
what is the role of cortisol?
helps maintain BP and cardiovascular function while reducing the body’s inflammatory responses
key role in glucose metabolism
what is the difference between Cushing syndrome, Cushing disease, and pseudo-Cushing syndrome?
Cushing syndrome: hypercortisolism resulting from adrenal gland over secretion or hyper-physiologic doses of corticosteroid medications
Cushing disease:
hypercortisolism is a result of over-secretion of ACTH
Pseudo-Cushing syndrome:
occurs when condition such as depression, alcoholism, estrogen therapy, or eating disorders cause changes like those in Cushing syndrome
what is the difference between Conn’s disease and Addison’s disease?
Conn’s disease is an increase in aldosterone
Addison’s disease is a decrease in aldosterone
