Adrenal Disorders Flashcards
1
Q
Causes of Primary Adrenal Insufficiency
A
- TB or fungal infection
- other dzs infiltrating adrenal gland
- hemorrhage
- idiopathic atrophy (autoimmune origin)
2
Q
Causes of Secondary Adrenal Insufficiency
A
- hypopituitarism due to HPA dz
- suppression of HPA axis by exogenous steroids
3
Q
Acute Adrenocortical Insufficiency
A
- adrenal crisis may occur from acute exacerbation of chronic insufficiency
- Waterhouse Frederickson syndrome
4
Q
Pt History in Adrenal Disorders
A
- weakness
- skin pigmentation
- weight loss
- abdominal pain
- D/C
- syncope
5
Q
Cushing’s Dz
A
-excess production of glucocorticoid hormones
6
Q
Etiology of Cushing’s
A
- iatrogenic: steroid therapy (MC cause)
- central: pituitary adenoma
- adrenal: adrenal adenoma or hyperplasia or malignancy
- ectopic source: malignancy
7
Q
Sxs of Cushing’s
A
- mood changes (depression, euphoria)
- easy bruising
- weakness
- weight gain
- menstrual changes
- back pain
8
Q
Signs of Cushing’s
A
- truncal obesity, moon facies, buffalo hump
- HTN
- glucose intolerance
- hirsutism
- wide purple abdominal striae
- osteoporosis
9
Q
Labs for Cushing’s
A
- low dose dexamethasone suppression test
- CT or MRI down sella turcica to check for pituitary adenoma
- CT abdomen for adrenal tumor
10
Q
Acromegaly
A
- rare dz that results from chronic exposure to growth hormone
- gigantism in youth, acromegaly in adults
- increased mortality over general population
11
Q
Etiology of Acromegaly
A
-pituitary adenoma
12
Q
Tx of Acromegaly
A
- surgical removal
- radiation
