Adrenal Cases Flashcards

1
Q

The hypercortisolism of Cushing’s syndrome is primarily treated by?

A

surgically

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2
Q

Pts with cushing and hepatotoxicity we should avoid?

A

Ketoconazole

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3
Q

Men should avoid ……. Of ttt cushing due to…….and……

A

Ketoconazole
induced gynecomastia and hypogonadism

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4
Q

Metyrapone is not suggested as the first-line drug for ….. due to …..

A

women
hirsutism and acne

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5
Q

Pts take pituitary irradiation what the adjunctive therapy should be used ?

A

Metyrapone

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6
Q

U can avoid Nausea and diarrhea of Mitotane by?

A

administering the agent with food.

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7
Q

Pregnant women with cusing she should avoid this medication due to its teratogenic effects?

A

Mitotane

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8
Q

Best combination?

A

Ketoconazole and metyrapone

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9
Q

Pts have cushing associated with urinary
free cortisol (UFC) its ttt is?

A

Cabergoline

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10
Q

Pts have cushing whom surgery has been unsuccessful they take this medication

A

Pasireotide

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11
Q

Se of Pasireotide

A

hyperglycemia

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12
Q

treatment of endogenous Cushing syndrome in patients who have type 2 diabetes or glucose intolerance, and who are not eligible for or have had poor response to surgery.

A

Mifepristone

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13
Q

During pregnancy, ————— is commonly used, while ————- must be avoided. Additionally, women desiring pregnancy within the next five years should avoid ————.

A

metyrapone
mifepristone
mitotane

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14
Q

———- is a clear second choice in women due to a high incidence of hirsutism, whereas ———— may be a secondary choice in men due to drug-induced gynecomastia and hypogonadism.

A

metyrapone
ketoconazole

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15
Q

——- is a leading cause of secondary hypertension and resistant hypertension.

A

Primary aldosteronism (PA)

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16
Q

———- is a substrate of CYP3A4 and should not be taken with potent CYP3A4 inhibitors.

A

Eplerenone

17
Q

Pts have problem in taking 3 times daily ttt for adison we give him?

A

Once-daily prednisolone