ACS Flashcards
Nitroglycerin indication
• Persistent ischemic chest pain
• Heart failure
• Hypertension
Nitroglycerin Contraindications
Sildenafil or vardenafil (use within 24 hr) or tadalafil (use within 48 hr)
• Systolic blood pressure < 90 mm Hg or ≥ 30 mm Hg below baseline
• Heart rate < 50 beats/min or heart rate > 100 beats/min
• Right ventricular infarction
BB indication they shouldn’t have
Hf
Low output
Cardiogenic shock
Avoid bb with ————— like——
sympathomimetic activity (acebutolol, pindolol, penbutolol)
STEMI Fibrinolytic
Clopidegrol
STEMI PCI & NSTMI INVASIVE
Prasugrel or Ticagrelor
Prasugrel CI for?
TIA AND STROKE
naïve pts should have ?
Cangrelor
Clopidogrel
1- loading dose?
2- maintenance dose?
3- prodrug or not?
4 reversible?
5- drug interaction?
6- surgery hold time?
7- bleeding risk?
8-ci?
1 300-600 mg
2 75mg
3 yes by two steeps
4 no
5 ppi
6 5 days
7 less one
8 nothing
Prasugrel
3- prodrug or not?
4 reversible?
5- drug interaction?
6- surgery hold time?
7- bleeding risk?
8-ci?
3 yes 1 step
4 no
5 no
6 7 days
8tia and stroke
Ticagrelor
3- prodrug or not?
4 reversible?
5- drug interaction?
6- surgery hold time?
7- bleeding risk?
8-ci?
3 no
4yes
5 aspirin if more than 100
6 3to5 days
Intracranial hemorrhage Severe hepatic disease
ACS managed medic
Cangrelor
Inter pact with
And dont with
Clopidogrel and prasugre
No such drug interaction exists with ticagrelor.
Abciximab reversed by
Eptifibatide and tirofiban reversed by
platelet transfusion
Cannot
If pts has heparin-induced thrombocytopenia we give him ?
Bivalirudin
Drug not used with pci
Fondaparinux