Adrenal

Question 1

Cushings MCC?

Answer 1

75% Endogenous (hyperplasia/hyperfunctioning tumors of the adrenal cortex), Exogenous (Cortisol medication), adrenal adenoma/carcinoma, neuroblastoma, pituitary neoplasm, ectopic tumors

Question 2

MC person in cushings?

Answer 2

20-60yo women

Question 3

Cushings s/sx?

Answer 3

easily bruise/purpura, menstural sx, obesity, weakness, emotional disturbance, backache, moon face, bufffalo hump, hypertension, abdominal/axillary purple striae. Children: short

Question 4

Cushings labs?

Answer 4

Leukocytosis, reduced glucose tolerance, enlarged renal glands and renal calculi (15-20%), hypercalciuria

Question 5

Cushings radiographic findings?

Answer 5

Osteoporosis, osteonecrosis

Question 6

Addisons sx?

Answer 6

Related to reduced aldosterone and cortisol.. weak, hypotension, hyperpigmentation, acidosis, etc…
May have migratory myalgias, back pain, and sciatica.

Question 7

Addisons radiographically?

Answer 7

Calcification of the adrenals, external ear, periarticular, and costal cartilages. Skeletal maturation may be delayed.