ADME Flashcards
1
Q
moving into bloodstream
A
absorption
2
Q
moving between blood and tissues
A
distribution
3
Q
conversion to more hydrophilic metabolites
A
metabolism
4
Q
strong acids vs weak acids
A
one way vs two way
5
Q
weak acid disassociation occurs more in ___ environment
A
basic
6
Q
acidic Rx in basic pH
A
ionized
7
Q
acid Rx in acidic pH
A
non-ionized, protonated
8
Q
pH > pKa = predominately ___ form
A
non-ionized, protonated
9
Q
ASA is excreted better in ___ urine
A
alkaline
10
Q
what form do LAs take in abscesses
A
ionized (due to acidic pH)
11
Q
depot injections are given ___
A
IM
12
Q
insulin and heparin are given ___
A
subQ
13
Q
TB tests and LAs are given ___
A
ID
14
Q
heart, brain, liver, kidney = ___ distribution
A
central
15
Q
SM and adipose = ___ distribution
A
peripheral
