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Term I: Histology > Adipose Tissue > Flashcards

Adipose Tissue Flashcards

1
Q

What are the functions of adipose tissue?

A

-Store energy -secrete hormones (Leptin) -Produce heat, insulate against heat loss -Protect against trauma -Barrier against infection

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2
Q

What is the function of brown adipose tissue?

A

Generate heat

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3
Q

What is the function of white adipose tissue?

A

Storage of neutral fat

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4
Q

What is the difference between neutral and non-neutral fat?

A

Neutral fat is totally hydrophobic. Non-neutral fat is amphipathic.

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5
Q

How do adipocytes synthesize neutral tryglycerides?

A
  1. Glucose–>Glycerol-3-P + 3 fatty acids –> triglycerides 2. Glucose–>acetate–>fatty acids Glucose–>Glycerol-3-P Glycerol-3-P + 3 fatty acids–>Triglyceride
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6
Q

What molecule transports free fatty acids in the blood stream?

A

Albumin

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7
Q

What does lipoprotein lipase do?

A

Breaks down fatty metabolites, releasing free fatty acids and glycerol so that they can diffuse into an adipocyte

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8
Q

What does Hormone sensitive lipase do?

A

hydrolyzes stored triglycerides to free fatty acids and glycerol

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9
Q

Where are brown adipocytes normally located?

A

-Neck area and interscapular region

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10
Q

What is a protein marker for brown adipocytes?

A

Uncoupling protein

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11
Q

Why is uncoupling protein a target for anti-obesity drugs?

A

it uncouples oxidative phosphorylation and ATP synthesis

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12
Q

Where is glucagon made?

A

Alpha cells of the pancreas

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13
Q

What does glucagon do?

A

raises blood glucose levels by signalling cells to degrade glycogen and triglycerides

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14
Q

What are two hormone hunger signals?

A

-Glucagon -Ghrelin

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15
Q

Where is ghrelin made?

A

GI tract

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16
Q

What does ghrelin do?

A

makes you hungry

17
Q

What are two hormones that signal satiety?

A

-Leptin -GLP-1

18
Q

Where is leptin made?

A

Adipocytes

19
Q

Where is GLP-1 produced?

A

GI tract

20
Q

What does GLP-1 do?

A

Tells you to stop eating, you’re full

21
Q

Which one of these strategies is likely to result in weight loss? A. Inhibiting Uncoupling Protein (UCP) B. Inhibiting hormone-sensitive lipase C. Activating lipoprotein lipase D. Activating uncoupling protein (UCP)

A

D. Activating UCP

22
Q

Is brown adipose tissue unilocular or multilocular?

A

Multilocular

23
Q

What is liipoprotien lipase made by?

A

Adipocytes

24
Q

What hormone activates lipoprotein lipase?

A

insulin

Term I: Histology (15 decks)

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