Adipose Tissue

Question 0

Initiates a series of metabolites steps that lead to activation of lipase

Answer 0

Norepinephrine

Question 1

When adipose tissue is stimulate by neural or hormonal mechanisms, TGs are broken down into glycerol and FA

Answer 1

Mobilization

Question 2

Enzyme that splits TGs which constitute more than 90% of the lipids stored in the adipocytes

Answer 2

Lipase

Question 3

Hormone that promotes lipid synthesis by stimulating lipid synthesis enzymes and supresses lipid degradation

Answer 3

Insulin

Question 4

Implicated as a Causative factor in the development of insulin resistance assoc. with obesity and diabetes

Answer 4

Tumor necrosis factor alpha

Question 5

Adipose tissue which helps offset the extensive heat loss and avoid lethal hypothermia

Answer 5

Brown adipose tissue

Question 6

Master switch regulator in the brown adiocyte’s differentiation

Answer 6

PRDM16/PGC-1

Question 7

A 33-Kd inner mitochondrial membrane protein that is essential for brown adipocyte metabolism

Answer 7

UPC-1

Question 8

An endocrine tumor of adrenal gland secreting excessive amounts of epinephrine and norepinephrine

Answer 8

Pheochromocytoma

Question 9

Most common benign tumor of adipose tissue

Answer 9

Lipoma

Question 10

Thermogenic activity of brown adipose tissue is facilitated by _____ that is found at the inner mitchondrial membrane

Answer 10

UPC-1

Question 11

Stimulates lipolysis and hydrolysis of TGs as well as increases mitochondrial expression and activity of UCP-1

Answer 11

Norepinephrine

Question 12

Cold stimulates glucose utilization in brown adipocytes by

Answer 12

Overexpression of glucose transporter (Glut-4)

Question 13

UCP-1 expression is unique to what adipose tissue?

Answer 13

Brown adipose tissue

Question 14

Unilocular, spherical, flatten nucleus, thin rim of cytoplasm

Answer 14

White adipose tissue

Question 15

Heat production (thermogenesis)

Answer 15

Brown adipose tissue