ADHD, ODD, CD Flashcards
What disorders are regularly co-morbid with ADHD?
ODD 20% to 30% CD 30% to 50% Anxiety 25% Depression 15-50% Learning disorder 10-90%
What is the history of ADHD?
Originally described as ‘defect in moral control’ (spiteful, lawless, jealous, dishonest, destructive, shameless, sexual immorality and viciousness)
At the end of WW1 there was minimal brain damage and attentional problems- so it was called Minimal Brain Damage disorder
Soon the behaviours continued but without evidence of brain damage, term changed to minimal brain dysfunction
DSM-III named it hyperkinetic reaction of childhood (didn’t talk about attention)
The next DSM-III added attention deficit
DSM-III-R replaced innattentive to undifferentiated adhd, the checklists were merged
DSM-5 : ADHD with 3 subtyped (predominately innatentive, predominatenyl hyperactive/impulsive, combined type)
Diagnostic criteria for ADHD
Inattention (6+) Makes careless mistakes Difficulty sustaining attention Doesn’t listen when spoken to Doesn’t follow instructions Difficulty organising tasks Avoids tasks requiring mental effort Loses things Easily distracted Forgetful Hyperactive/impulsive – at maladaptive levels for at least last 6 months (6+) Fidgets Leaves seat when required to sit Inappropriately runs or climbs Difficulty playing Often ‘on the go’ Talks excessively Bursts out answers Difficulty waiting turn Interrupts others
Extra conditions for diagnosis
Behaviours present before 12 yrs
In DSM-4 had to be present before the age of 7
Moved the age of onset older so that people could remember when making an adult diagnosis
Impairment present in 2 or more settings
Clear evidence of impairment (social, academic) + vocationally in adults
Does not exclusively occur during course of schizophrenia, other psychotic disorder
Consider this when assessing adults
Not better accounted for by other mental disorder (i.e. mental retardation)
Adam suggests running an IQ on almost everyone with behavioural concerns, to see if there are problems of mental retardation
Prevalence of ADHD
ADHD is the most common childhood psychiatric disorder in clinical practice.
5-9% prevalence
More common in males
Hyperactivity is more likely to present as hyper-talkativeness in females
ADHD in adults
40-60% childhood sufferers have ADHD as adults
Hyperactivity often decreases, but impulsivity and innattention remains
ADHD and psychosis
Preliminary studies suggest that childhood ADHD may be a precursor to adult psychosis
Maturational lag hypothesis
ADHD is marked by slower development of the central nervous system
This model doesn’t work for inattention, only hyperactivity
Cortical hypoarousal model
CNS is underaroused (hence why stimulants work)
Hyperactivity is an attempt to increase sensory input to normal levels
This model still holds
Inhibitory deficit model/executive function deficit model
Inhibition deficit is primary, there are impaired executive functions (working memory, self regulation of affect, motivation, arousal) and motoric control problems
Cognitive energetic model
Efficacy of information processing is determined by the interplay of attention, state factors and management/executive function.
Attention includes: encoding, search, decision making and motor organisation.
State factors include; effort, arousal and activation
Arousal is a tonic measure, activation is a phasic measure
EF’s: planning monitoring, detection of errors, error correction
All 3 levels interact to form deficits in ADHD
ADHD Medication
Medication is by far the most effective, and stimulants work for 80+% of children
Methylphenidate Hydrochloride: Ritalin, Ritalin LA, Concerta, Attenta
mode of action in humans is not completely understood, but methylphenidate presumably exerts its stimulant effect by activating the brainstem arousal system and cortex
Increases dopamine in the synaptic cleft
Dexamphetamine (cheaper than Ritalin)
Atomoxetine hydrochloride: Strattera, inhibitor of the presynaptic noradrenaline transporter- A non-stimulant which means that it is less controlled in most countries
Clonidine Hydrochloride : hypertensive, used to help with sleep and conduct disorder
Neurofeedback
Aims to normalise abnormal brain activity in children
Conducted as continuous feedback or using operant conditioning principals to normalise brainwave activity
Mixed results in the literature
Randomised controlled double blinded trials showed no benefit of neurofeedback vs placebo
ADHD and diet
Will aid approx 5% of children with ADHD
Elimination died
ADHD: Behaviour modification and therapy
Positive reinforcement does work
Family therapy: doesn’t fix core symptoms but will work for associated problems
Cognitive therapies: will do nothing for core symptos, but can treat peripheral problems again