ADHD

Question 1

What’s the genetic heritability of adhd?

Answer 1

75-91%

Question 2

How is ADHD thought related to prefrontal lobe dysfunction?

Answer 2

since prefrontal lobe regulates working memory, and working memory keeps info in conscious awareness & directs processing.

Question 3

What happens when there’s dysfunction in the prefrontal lobe?

Answer 3

working memory decreases, there are no guided thoughts/bx and no regulated attention or monitoring actions.

Question 4

What is used to treat adhd?

Answer 4

Dopamine agonists: since it’s related to underactivity of dopamine.

Question 5

What does animal research show in levels of PFC?

Answer 5

Indicates that stimulants increased dopamine (and norepinephrine) levels in PFC but not in other brain regions. This suggests dopamine pathway in pfc involved in adhd.

Question 6

What happens to the cortical growth and thickness in adhd?

Answer 6

Cortical growth delayed in adhd and cortical thickness of adhd at age 10 is equal to normal age 7.

Question 7

Which network of brain is adhd involved in?

Answer 7

It is related to abnormalities involving the straitum (i.e., caudate and putamen) and prefrontal cortex.

Question 8

What does fMRI show in ADHD patients?

Answer 8

fMRI show decreased activity in caudate or medial prefrontal cortex in adhd’s when performing task requiring attention and response inhibition.