Adenovirus Flashcards
Characteristics
Non enveloped, resistant to inactivation
What is type 1 and type 2 called?
Hepatitis, tracheobronchitis
What happens in type 1
disease umcommon where immunization is present, survives outside for weeks to months. Targets vascular endothelial cells
What are the clinical signs?
acute: slight fever to death
What’s the progressive CAV1?
Endothelial compromise, reduced liver function, petechiae on mucous membranes, coagulopathy, leukopenia. Widespread hemorrhage
Lesions of CAV1?
hepatic cell swelling and necrosis. edematous thickening of gall bladder wall,
What;s the chronic disease of CAV1?
chronic kidney lesions and ocular opacities in the cornea, 25% get bilateral opacities.
Treatment and prognosis
10-30% mortality.
What causes kennel cough?
canine parainfluenza, canine adenovirus, canine distemper, bordetella.
Clinical signs of CAV2?
harsh and dry cough, 5-10 day incubation period, disease can last 10-20 days. Highly contagious.
Diagnosis and treatment
PCR, MLV vx, cross protects against CAV1, core vaccine
Equine adenovirus
high seroprevalence, 1 with respiratory infections and 2 with GI infections.
Clinical signs and lesions in Equine 1
subclinical and inapparent, associated with SCID in arabian foals. PCR.
Canine respiratory coronavirus
No vaccine available, contributes to kennel cough.
Equine rotavirus
foal diarrhea, morbidity is high, risk based vaccine, administer to pregnant mares. Foals less than 2 months, colostrum needed