Adenovirus Flashcards
Infect mamals
Mastadenovirus
Infect birds
Aviadenovirus
Atleast how many proteins
11
•Relatively stable, remaining viable for about a week at
37 degree Celsius
Are readily inactivated at
50 degree Celsius
Resist using
Ether and bile salt
Disease Mechanisms of Adenoviruses:
Virus is spread by aerosol, close contact, or fecal-oral means to establish__________________. Fingers spread virus to eyes.
pharyngeal infection
Disease Mechanisms of Adenoviruses:
Virus infects mucoepitheal cells in the ______________ tract, _____________ tract, and __________ or _________, causing cell damage directly.
respiratory tract, gastrointestinal tract, and conjunctiva or cornea
Disease Mechanisms of Adenoviruses:
Virus persists in __________ tissue
lymphoid tissue
Disease Mechanisms of Adenoviruses:
is important for prophylaxis and resolution but cell-mediated immunity is also important.
Antibody
Epidemiology of Adenoviruses: Disease/Viral Factors
Capsid virus is resistant to inactivation by gastrointestinal tract and drying
Disease symptoms may resemble those of other respiratory virus infections
Virus may cause asymptomatic shedding
Epidemiology of Adenoviruses: Transmission
Direct contact via respiratory droplets and fecal matter, on hands, on fomites
Epidemiology of Adenoviruses: Who Is at Risk?
Children younger than 14 years of age
People in crowded areas
Epidemiology of Adenoviruses: Geography/Season
Virus is found worldwide
There is no seasonal incidence
Epidemiology of Adenoviruses: Modes of Control
Live vaccine for serotypes 4 and 7 is available for military use