Adenosine

Question 1

Mechanism of Adenosine

Answer 1

Transient AV nodal blockade

Question 2

How does adenosine act upon the AV node?

Answer 2

Transient heart block by inhibiting a-1 receptor, stopping adenyl cyclase.

Question 3

Indication of adenosine.

Answer 3

PSVT

Question 4

Adult dosage of adenosine.

Answer 4

6 mg rapid IVP with 10 cc NS flush
12 mg rapid IVP with 10 cc NS flush

May repeat once.

Question 5

Contraindications of adenosine.

Answer 5

Allergy;
2*/3* heart block;
Sick sinus w/o pacemaker;
Long QTc;
HypoTN