Additional Drugs with Narrow therapeutic index 2 Flashcards

1
Q

A medication used to treat life threatening ventricular arrhythmias

A

Procainamide

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2
Q

An antiepileptic agent used for the management of generalized convulsive status epilepticus and prevention and treatment of seizures occurring during neurosurgery.

A

Fosphenytoin

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3
Q

An aminoglycoside used to treat a wide variety of aerobic infections in the body.

A

Gentamycin

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4
Q

A medication used to treat manic episodes of bipolar disorder.

A

Lithium carbonate

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5
Q

A calcineurin inhibitor used to prevent organ transplant rejection and to treat moderate to severe atopic dermatitis.

A

Tacrolimus

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6
Q

An mTOR inhibitor immunosuppressant used to prevent organ transplant rejections, treat lymphangioleiomyomatosis, and treat adults with perivascular epithelioid cell tumors.

A

Sirolimus

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7
Q

A antineoplastic agent used in the treatment of renal cell carcinoma (RCC) that works by inhibiting mTOR.

A

Temsirolimus

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8
Q

A barbiturate used to induce general anesthesia, treat convulsions, and reduce intracranial pressure.

A

Thiopental

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9
Q

An antipsychotic used to manage debilitating motor and phonic tics in patients with Tourette’s Disorder.

A

Pimozide

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10
Q

A medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.

A

Quinidine

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11
Q

An anticoagulant indicated for thromboprophylaxis and to treat thrombosis associated with a variety of conditions such as pulmonary embolism and atrial fibrillation.

A

Heparin

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12
Q

A glycopeptide antibiotic used to treat severe but susceptible bacterial infections such as MRSA (methicillin-resistant Staphylococcus aureus) infections.

A

Vancomycin

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13
Q

A bronchodilator consisting of theophylline that is used for the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis.

A

Aminophylline

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14
Q

An aminoglycoside used to treat infections caused by more resistant strains of Gram negative bacteria and some Gram positive bacteria.

A

Amikacin

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15
Q

An antifungal used to treat fungal infections in neutropenic patients, cryptococcal meningitis in HIV infection, fungal infections, and leishmaniasis.

A

Amphotericin B

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16
Q

An anticonvulsant used to control complex partial seizures and both simple and complex absence seizures.

A

Valproic acid

17
Q

A class III antiarrhythmic indicated for the treatment of recurrent hemodynamically unstable ventricular tachycardia and recurrent ventricular fibrillation.

A

Amiodarone

17
Q

A class III antiarrhythmic drug used for the maintenance of normal sinus rhythm and cardioversion in cases of atrial fibrillation and atrial flutter.

A

Dofetilide

18
Q

A methane sulfonanilide beta adrenergic antagonist used to treat life-threatening ventricular arrhythmias and to maintain sinus rhythm in atrial fibrillation or flutter.

19
Q

A synthetic direct thrombin inhibitor used for the prevention and treatment of thrombosis related to heparin use.

A

Argatroban

20
Q

A mammalian target of rapamycin (mTOR) kinase inhibitor used to treat various types of malignancies.

A

Everolimus

21
Q

An immunosuppressant used to prevent organ transplant rejections.

A

Mycophenolic acid

22
Q

is a tricyclic antidepressant which has been used in Europe since 1974. It is the isobutyl side chain homologue of amitriptyline

A

Butriptyline

23
Q

A tricyclic antidepressant indicated in the treatment of depressive disorders.

A

Amitriptylinoxide

24
For the treatment of depression.
Amineptine
25
A tricyclic antidepressant commonly used only in patients for whom alternative therapies are ineffective due to its toxicity potential.
Dosulepin
26
An atypical tricyclic antidepressant with antidepressant and anxiolytic effects primarily used to treat major depressive disorder.
Tianeptine
27
An aminoglycoside antibiotic agent used orally and topically to treat a wide variety of infections in the body.
Neomycin
28
An aminoglycoside antibiotic indicated to treat multi-drug resistant mycobacterium tuberculosis and various non-tuberculosis infections.
Streptomycin
29
An aminoglycoside used to treat a wide variety of infections in the body.
Netilmicin