Additional Flashcards

1
Q

Most breast cancers are diagnosed after the age of:

A

50

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2
Q

Invasive breast Lesions

A

Invasive Ductal carcinoma
(5subtypes)
Paget’s disease of the nipple
Invasive lobular carcinoma
Metaplastic carcinoma
Adenoid cystic carcinoma
Inflammatory breast carcinoma
Malignant Phyllodes tumor
Metastatic breast carcinoma

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3
Q

5 sub types of Invasive Ductal Carcinoma

A

Invasive Ductal Carcinoma NOS
Medullary carcinoma
Mucinous (or Colloid) Carcinoma
Tubular carcinoma
Papillary carcinoma

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4
Q

Medullary Carcinoma:

A

Is more common in Japanese and black patients
More common in younger women than elderly
Often confused with fibroadenoma
Grows quickly

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5
Q

Invasive Ductal carcinoma NOS

A

Makes up the largest group at 65-75% of all invasive mammary carcinomas
Worst prognosis of the invasive carcinomas
More common in older women

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6
Q

Mucinous (Colloid) carcinoma

A

Rare
Formed by mucous producing cancer cells
More common in older women
Slow growing
Display posterior acoustic enhancement

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7
Q

Tubular carcinoma

A

occurs in median age patients. Between 44-49 years
Associated with foci of DCIS
Multifocal disease if common

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8
Q

Papillary carcinoma

A

May be invasive or noninvasive
Slow growing
Appear in older patients 63-67
Bloody nipple discharge is the most common symptom
Most commonly found in the subareolar region

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9
Q

Paget’s disease of the nipple

A

Originating as DCIS
Limited to the nipple/areola
Symptoms include: pain, itchiness, scaling, erythema, bloody discharge

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10
Q

Invasive lobular carcinoma

A

2nd most common type of invasive tumor
Cells infiltrate in a uniform linear arrangement
May be bilateral or unilateral

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11
Q

Metaplastic carcinoma

A

Contains glandular and nonglandular patterns
Aggressive
Poor prognosis
Heterogeneous, hypoechoic, can contain complex cystic and solid components

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12
Q

Adenoid cystic carcinoma

A

Rare
Excellent prognosis
Uncommon for Mets or axillary node involvement

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13
Q

Inflammatory breast carcinoma

A

Poor prognosis
Grows and spreads rapidly
(Die within 2 years)
Symptoms similar to mastitis
Peau d’orange
Dilated subdermal lymphatics

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14
Q

Malignant Phyllodes tumor

A

25% of Phyllodes become malignant
Size greater than 3cm
Mixed echo texture with cystic spaces
Present in older patients
More prone to spread to the lungs, liver and other distant locations

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15
Q

Lymphoma

A

B cell origin( Non-Hodgkin lymphoma)
Burkitt’s Lymphoma (more common) found in pregnant or lactating women. Poor prognosis

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16
Q

Breast cancer most frequently spreads by:

A

Hematogenous route

17
Q

Estrogen stimulates changes of the

A

Stromal tissues

18
Q

Progesterone stimulates growth of the

A

Glandular tissues
(TDLU)