Addison's disease

Question 1

What is Addison’s disease?

Answer 1

adrenal cortex insufficiency

Results in diffuse hypermelanosis. Multiple circumscribed dark brown-black macules covered with intact mucosa.

Question 2

Does lesions from Addison’s disease manifest in the oral cavity?

Answer 2

Any oral mucosa can be involved

Question 3

What is the clinical appearance of Addison’s disease lesions?

Answer 3

Generalized brown pigmentation of sun exposed skin (bronzin of the skin)

Question 4

Symptoms of Addison’s disease?

Answer 4

Anorexia

Nausea

Vomiting

Fatigue

Irritability

Depression

Weakness

Hypotension

Question 5

What is typically the first indication of Addison’s disease?

Answer 5

Oral mucosal lesions

Question 6

What is the tx for oral lesions from Addison’s disease?

Answer 6

No Tx necessary for oral lesions

Question 7

Tx for Addison’s disease?

Answer 7

Corticosteroid replacement