Addison And cushing Flashcards

1
Q

Inadequate corticosteroid and mineralocorticoid synthesis
Which disease

A

Addison disease

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2
Q

Elevated ACTH levels
What disorder

A

Addison

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3
Q

Symptoms of Addison disease are a result of what two conditions

A

Hypocortisolism
Hypoaldosteronism

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4
Q

Hypocortisolism
Hypoaldosteronism
What condition

A

Addison

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5
Q

Hypocortisolism
What condition

A

Addison

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6
Q

Hypoaldosteronism
What condition

A

Addison

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7
Q

Aldosterone’s primary function is to act on what organ

A

Kidney

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8
Q

What hormone?
Favors sodium and water reabsorption and potassium excretion

A

Aldosterone

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9
Q

What two things does aldosterone favor resorption?

A

Sodium
Water

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10
Q

Aldosterone favors excretion of what

A

Potassium

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11
Q

Hyperkalemia in Addison is a result of what

A

Not enough aldosterone

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12
Q

Why is there hyperkalemia in Addison disease?

A

Not enough aldosterone

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13
Q

Hypovolemia in Addison disease why?

A

Not enough aldosterone

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14
Q

All clinical manifestations related to excessive exposure to cortisol

A

Cushing syndrome

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15
Q

Hypokalemia
Cushing or Addison

A

Cushing

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16
Q

Hyperkalemia
Cushing or Addison

17
Q

Hyperglycemia or hypoglycemia in Cushing

A

Hyperglycemia

18
Q

Sodium imbalance in Cushing?
Think opposite of Addison

A

Hypernatremia

19
Q

Potsssium imbalance in Addison?

A

Hyperkalemia

20
Q

Potassium imbalance in Cushing?

A

Hypokalemia

21
Q

Three signs (physical) of Cushing

A

Truncal obesity
Moon face
Buffalo hump

22
Q

Cortisol induced insulin resistance leads to what type of intolerance

23
Q

Why is there hyperglycemia in Cushing syndrome?

A

Increased gluconeogenesis and glycogen storage by the liver

24
Q

Increased gluconeogenesis and glycogen storage by the liver lead to what in Cushing?

A

Hyperglycemia

25
Catabolic effects of cortisol on peripheral tissues is caused by what in Cushing
Protein wasting
26
Where is muscle wasting in Cushing most prominent?
Muscles of extremities Thinning of limbs
27
Thin weakened integumentary tissues are due to loss of what
Collagen
28
Exogenous Cushing like syndrome due to what
Long term administration of glucocorticoids
29
Purple striae and easy bruising What condition
Cushing
30
Loss of what leads to purple striae and easy bruising?
Collagen